Cardiovascular disease (CVD) is the leading cause of death worldwide and originates in
early life. The exact mechanisms of this early-life origin are unclear, but a likely mediator at …

Objective: The purpose of this study was to undertake a comprehensive review to identify all
the available preclinical and clinical literature investigating cardiovascular and renal …

Background: Ethanol (EtOH) consumption during pregnancy can lead to fetal growth
retardation, mental retardation, and neurodevelopmental delay. The fetal brain initiates …

Alcohol (ethanol [EtOH]) is one of the most widely used psychoactive substances worldwide.
Alcohol consumption during pregnancy may result in a wide range of morphological and …

(1) Background: Programming of atherosclerosis results in vascular structure and function
alterations, which may be attributed to fetal exposure to maternal tobacco smoking, alcohol …

Fetal alcohol spectrum disorder (FASD) is a significant public health issue in Australia that is
poorly diagnosed, chronic and costly. FASD is a diffuse acquired brain injury secondary to …

Background The vascular system may be particularly vulnerable to prenatal alcohol
exposure (PAE). Alterations in angiogenesis and epigenetic changes to vascular …

Low to moderate alcohol intake has been associated with beneficial effects on the heart and
the vasculature, including improvements in several established and emerging …

Background Exposure to an adverse environment in early life can have lifelong
consequences for risk of cardiovascular disease. Maternal alcohol (ethanol) intake is …

Prenatal alcohol exposure (PAE) is often associated with congenital heart defects, most
commonly septal, valvular, and great vessel defects. However, there have been no known …