The brain and immune system prompt energy shortage in chronic inflammation and ageing

RH Straub - Nature Reviews Rheumatology, 2017 - nature.com
Sequelae frequently seen in patients with chronic inflammatory diseases, such as fatigue,
depressed mood, sleep alterations, loss of appetite, muscle wasting, cachectic obesity, bone …

Exercise and chronic pain

A Borisovskaya, E Chmelik, A Karnik - Physical exercise for human health, 2020 - Springer
In this chapter, we describe the impact and etiology of chronic pain, the associated changes
in the nervous system, and the mechanisms by which exercise may be able to affect and …

Genome-wide association study of multisite chronic pain in UK Biobank

KJA Johnston, MJ Adams, BI Nicholl, J Ward… - PLoS …, 2019 - journals.plos.org
Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and
public health burden. Several aspects of chronic pain, for example back pain and a severity …

Body mass index and distribution of body fat can influence sensory detection and pain sensitivity

OA Tashani, R Astita, D Sharp… - European Journal of …, 2017 - Wiley Online Library
Background The aim of this study was to investigate the influence of body fat percentage
and its distribution on sensory detection and pain sensitivity responses to experimentally …

Emerging relationships between exercise, sensory nerves, and neuropathic pain

MA Cooper, PM Kluding, DE Wright - Frontiers in neuroscience, 2016 - frontiersin.org
The utilization of physical activity as a therapeutic tool is rapidly growing in the medical
community and the role exercise may offer in the alleviation of painful disease states is an …

Pain in people with multiple sclerosis: associations with modifiable lifestyle factors, fatigue, depression, anxiety, and mental health quality of life

CH Marck, AM De Livera, TJ Weiland… - Frontiers in …, 2017 - frontiersin.org
Background People with multiple sclerosis (MS) often experience pain, which can interfere
with mobility, employment, and quality of life (QOL). Methods This cross-sectional study …

[HTML][HTML] Conditioned pain modulation and pressure pain sensitivity in the adult Danish general population: the DanFunD study

S Skovbjerg, T Jørgensen, L Arendt-Nielsen… - The Journal of …, 2017 - Elsevier
Increased pressure pain sensitivity and impaired descending pain control have been
associated with chronic pain, but knowledge on the variability in the adult general …

Factors associated with life satisfaction in older adults with chronic pain (PainS65+)

HJ Dong, B Larsson, E Dragioti, L Bernfort… - Journal of Pain …, 2020 - Taylor & Francis
Background Chronic pain in later life is a worldwide problem. In younger patients, chronic
pain affects life satisfaction negatively; however, it is unknown whether this outcome will …

Physiological changes and pathological pain associated with sedentary lifestyle-induced body systems fat accumulation and their modulation by physical exercise

E Verdú, J Homs, P Boadas-Vaello - International journal of …, 2021 - mdpi.com
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Obesity hurts: the why and how of integrating weight reduction with chronic pain management

A Malfliet, A Quiroz Marnef, J Nijs, P Clarys… - Physical …, 2021 - academic.oup.com
Amongst adults with chronic pain, overweight and obesity are highly prevalent. The
association between chronic pain and overweight is driven by several explanations …