Applications of cucurbiturils in medicinal chemistry and chemical biology

D Das, KI Assaf, WM Nau - Frontiers in chemistry, 2019 - frontiersin.org
The supramolecular chemistry of cucurbit [n] urils (CB n) has been rapidly developing to
encompass diverse medicinal applications, including drug formulation and delivery …

Cucurbit [7] uril: an emerging candidate for pharmaceutical excipients

KI Kuok, S Li, IW Wyman… - Annals of the New York …, 2017 - Wiley Online Library
Cucurbit [7] uril (CB [7]), belonging to the cucurbit [n] uril family (CB [n], n= 5–8, 10, or 13–
15), may form host–guest complexes with a variety of small molecules of biomedical interest …

Kinetics inside, outside and through cucurbiturils

E Masson, M Raeisi, K Kotturi - Israel Journal of Chemistry, 2018 - Wiley Online Library
This review describes the kinetics at play in Cucurbituril (CB [n])/guest recognition within a
very wide time frame, from picoseconds to days. We cover the kinetics of (1) radiative and …

Cucurbituril-oriented nanoplatforms in biomedical applications

G Cheng, J Luo, Y Liu, X Chen, Z Wu… - ACS Applied Bio …, 2020 - ACS Publications
Cucucrbituril (CB) belongs to a family of macrocycles that are easily accessible. Their
structural specificity provides excellent molecular recognition capabilities, with the ability to …

Sequence-specific self-assembly of positive and negative monomers with cucurbit [8] uril linkers

M Raeisi, K Kotturi, I Del Valle, J Schulz… - Journal of the …, 2018 - ACS Publications
The self-assembly into dynamic oligomers of Cucurbit [8] uril (CB [8]), a positive ditopic Ir (III)
bis-terpyridine complex, and a negative ditopic Fe (II) bis-terpyridine complex flanked by four …

Supramolecularly assisted chlorhexidine-bacterial membrane interaction with enhanced antibacterial activity and reduced side effects

YR Ruan, WZ Li, YY Ye, J Luo, SY Xu, J Xiao… - Journal of Colloid and …, 2023 - Elsevier
Bacterial infection has emerged as a grievous threat to public health, and lots of antibacterial
agents were developed to solve this issue. However, enhancing the antibacterial activity of …

Comparison of Complexation-Induced pKa Shifts in the Ground and Excited States of Dyes as Well as Different Macrocyclic Hosts and Their Manifestation in Host …

AI Lazar, J Rohacova, WM Nau - The Journal of Physical …, 2017 - ACS Publications
1-Aminopyrene and 1-naphthylamine-5-sulfonic acid were converted to the putrescine (1, 4-
diaminobutane)-substituted derivatives (dyes 1 and 2). The diaminobutyl anchor serves as a …

Cucurbit [n] uril Host‐Guest Complexes of Acids, Photoacids, and Super Photoacids

DH Macartney - Israel Journal of Chemistry, 2018 - Wiley Online Library
The supramolecular chemistry of host‐guest complexes of cucurbit [n] urils (CB [n]) with
acidic guests in the ground (HG+) and excited states (HG+*) are reviewed. The effects of CB …

Supramolecular and suprabiomolecular photochemistry: a perspective overview

SD Choudhury, H Pal - Physical Chemistry Chemical Physics, 2020 - pubs.rsc.org
In this perspective review article, we have attempted to bring out the important current trends
of research in the areas of supramolecular and suprabiomolecular photochemistry. Since …

Supramolecular encapsulation of a neurotransmitter serotonin by cucurbit [7] uril

F Chandra, T Dutta, AL Koner - Frontiers in Chemistry, 2020 - frontiersin.org
pH-dependent host-guest complexation of a monoamine neurotransmitter, Serotonin, with
cucurbit [7] uril has been thoroughly investigated. The binding phenomena were explored …