The heat-shock response, one of the main pro-survival mechanisms of a living organism,
has evolved as the biochemical response of cells to cope with heat stress. The most well …

Sterile neuroinflammation is essential for the proper brain development and tissue repair.
However, uncontrolled neuroinflammation plays a major role in the pathogenesis of various …

Importance Induced hypothermia, the standard treatment for hypoxic-ischemic
encephalopathy (HIE) in high-income countries (HICs), is less effective in the low-income …

Mitochondrial dysfunction has been suggested to contribute to Parkinson's disease
pathogenesis, though an understanding of the extent or exact mechanism of this contribution …

Alzheimer's disease (AD) is an aging-related multi-factorial disorder to which metabolic
factors contribute at what has canonically been considered a centrally mediated process …

Understanding the interplay between the innate immune system, neuroinflammation, and
epilepsy might offer a novel perspective in the quest of exploring new treatment strategies …

Synthetic cannabinoids and phytocannabinoids have been shown to suppress seizures both
in humans and experimental models of epilepsy. However, they generally have a …

The identification of a reliable and accurate post-mortem interval (PMI) is a major challenge
in the field of forensic sciences and criminal investigation. Several laboratory techniques …

Hsp60 is a molecular chaperone classically described as a mitochondrial protein with
multiple roles in health and disease, participating to the maintenance of protein …

Background: Alzheimer's disease (AD) is a dementia, a neurodegenerative condition, and a
protein-misfolding disease or proteinopathy, characterized by protein deposits, extracellular …