Salvia divinorum is a perennial sage native to Oaxaca, Mexico, that has been used
traditionally in divination rituals and as a treatment for the “semimagical” disease panzón de …

The plant metabolite salvinorin A potently and selectively agonizes the human kappa-opioid
receptor, an emerging target for next-generation analgesics. Here we review analogs of the …

The opium poppy, PapaVer somniferum, is one of several plants that have profoundly
affected human history. 1 It has provided an unmatched medicine for the relief of pain for …

Two clerodane diterpenoids, Bafoudiosbulbins A 1, and B 2, together with five known
compounds: tetracosanoic acid, 1-(tetracosanoyl)-glycerol, trans-tetracosanylferulate, β …

Covering: 2005. Previous review: Nat. Prod. Rep., 2005, 22, 594 This review covers the
isolation and structures of diterpenoids, including labdanes, clerodanes, pimaranes …

Traditional Chinese medicine (TCM) has played important roles in health protection and
disease treatment for thousands of years in China and has gained the gradual acceptance …

Urinary metabolic perturbations associated with liver toxicity induced by Huang-yao-zi (root
of Dioscorea bulifera L.) were studied using nuclear magnetic resonance spectroscopy (1H …

The hallucinogenic plant Salvia divinorum (ie,“magic mint”) is a member of the Sage family
that has been used for divination and shamanism by the Mazatecs. Over the past decade or …

Previous structure–activity relationship (SAR) studies identified the first centrally acting, non-
nitrogenous μ-opioid receptor (MOR) agonist, kurkinorin (1), derived from salvinorin A. In an …

Salvinorin A is a psychoactive natural product that has been found to be a potent and
selective κ opioid receptor agonist in vitro and in vivo. The activity of salvinorin A is unusual …