MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

FOXO proteins are transcription factors that are involved in numerous physiological
processes and in various pathological conditions, including cardiovascular disease, cancer …

Many transcription factors play a key role in cellular differentiation and the delineation of cell
phenotype. Transcription factors are regulated by phosphorylation, ubiquitination …

MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

The increased incidence of cardiovascular diseases (CVDs) has stimulated research for
substances that could improve cardiovascular health. Among them, resveratrol (RES), a …

Forkhead box O (FOXO) transcription factors are involved in the regulation of the cell cycle,
apoptosis and metabolism. In model organisms, FOXO activity also affects stem cell …

Targeting RNAs with small molecules represents a new frontier in drug discovery and
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …