The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

The dopamine (DA) transporter (DAT) controls the spatial and temporal dynamics of DA
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …

Restless legs syndrome (RLS), also known as Willis–Ekbom Disease (WED), is a
sensorimotor disorder for which the exact pathophysiology remains unclear. Brain iron …

J. Neurochem.(2011) 116, 164–176. Abstract It is now recognized that trace amine
associated‐receptor 1 (TAAR1) plays a functional role in the regulation of brain …

Adenosine plays a very significant role in modulating striatal glutamatergic and
dopaminergic neurotransmission. In the present essay we first review the extensive …

Drug addiction has been associated with deficits in mesostriatal dopamine (DA) function, but
whether this state extends to behavioral addictions such as pathological gambling (PG) is …

Dopaminergic signaling in the brain is primarily modulated by dopamine transporters
(DATs), which actively translocate extraneuronal dopamine back into dopaminergic …

Tourette syndrome (TS) is thought to involve dopaminergic disturbances, but the nature of
those disturbances remains controversial. Existing hypotheses suggest that TS involves 1) …

The dynorphin/κ-opioid receptor system has been implicated in the pathogenesis and
pathophysiology of several psychiatric disorders. In the present review, we present evidence …

Presynaptic biogenic amine transporters mediate reuptake of released amines from the
synapse, thus regulating serotonin, dopamine and norepinephrine neurotransmission …