Deep learning-enabled virtual histological staining of biological samples
Histological staining is the gold standard for tissue examination in clinical pathology and life-
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
Artificial intelligence for digital and computational pathology
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …
including deep learning, have boosted the field of computational pathology. This field holds …
Virtual formalin-fixed and paraffin-embedded staining of fresh brain tissue via stimulated Raman CycleGAN model
Intraoperative histology is essential for surgical guidance and decision-making. However,
frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy …
frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy …
Deep learning-based virtual staining, segmentation, and classification in label-free photoacoustic histology of human specimens
In pathological diagnostics, histological images highlight the oncological features of excised
specimens, but they require laborious and costly staining procedures. Despite recent …
specimens, but they require laborious and costly staining procedures. Despite recent …
Clinical translation of photoacoustic imaging
Photoacoustic imaging (PAI), also known as optoacoustic imaging, is a promising
biomedical imaging technique that combines the benefits of rich optical contrast and high …
biomedical imaging technique that combines the benefits of rich optical contrast and high …
Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues,
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
Noninvasive virtual biopsy using micro-registered optical coherence tomography (OCT) in human subjects
Histological hematoxylin and eosin–stained (H&E) tissue sections are used as the gold
standard for pathologic detection of cancer, tumor margin detection, and disease diagnosis …
standard for pathologic detection of cancer, tumor margin detection, and disease diagnosis …
Ultrafast longitudinal imaging of haemodynamics via single-shot volumetric photoacoustic tomography with a single-element detector
Techniques for imaging haemodynamics use ionizing radiation or contrast agents or are
limited by imaging depth (within approximately 1 mm), complex and expensive data …
limited by imaging depth (within approximately 1 mm), complex and expensive data …
Label-and slide-free tissue histology using 3D epi-mode quantitative phase imaging and virtual hematoxylin and eosin staining
Histological staining of tissue biopsies, especially hematoxylin and eosin (H&E) staining,
serves as the benchmark for disease diagnosis and comprehensive clinical assessment of …
serves as the benchmark for disease diagnosis and comprehensive clinical assessment of …
Virtual multiplexed immunofluorescence staining from non-antibody-stained fluorescence imaging for gastric cancer prognosis
Background Multiplexed immunofluorescence (mIF) staining, such as CODEX and MIBI,
holds significant clinical value for various fields, such as disease diagnosis, biological …
holds significant clinical value for various fields, such as disease diagnosis, biological …