Definition and epidemiology of treatment-resistant depression

M Fava, KG Davidson - Psychiatric Clinics of North America, 1996 - Elsevier
The main goal of treatment in patients with mood disorders is usually to restore a state of
psychological wellness and high functioning. Although many depressed patients do improve …

Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating …

GI Papakostas, ME Thase, M Fava, JC Nelson… - Biological …, 2007 - Elsevier
BACKGROUND: Recent studies suggest that the treatment of major depressive disorder
(MDD) with newer antidepressant drugs that simultaneously enhance norepinephrine and …

Moclobemide: therapeutic use and clinical studies

U Bonnet - CNS drug reviews, 2003 - Wiley Online Library
Moclobemide is a reversible inhibitor of monoamine‐oxidase‐A (RIMA) and has been
extensively evaluated in the treatment of a wide spectrum of depressive disorders and less …

The role of monoamine oxidase inhibitors in current psychiatric practice

JG Fiedorowicz, KL Swartz - Journal of Psychiatric Practice®, 2004 - journals.lww.com
The use of monoamine oxidase inhibitors (MAOIs) by psychiatrists has declined over the
past several decades with the expansion of psychiatrists' pharmacologic armamentarium …

Meta-analysis of the reversible inhibitors of monoamine oxidase type A moclobemide and brofaromine for the treatment of depression

F Lotufo-Neto, M Trivedi, ME Thase - Neuropsychopharmacology, 1999 - Elsevier
The reversible inhibitors of monoamine oxidase type A (RIMAs) are a newer group of
antidepressants that have had much less impact on clinical psychopharmacology than …

Fluoxetine versus other types of pharmacotherapy for depression

A Cipriani, P Brambilla, TA Furukawa… - Cochrane Database …, 2005 - cochranelibrary.com
Background Depression is common in primary care and it is associated with marked
personal, social and economic morbidity, and creates significant demands on service …

Fluoxetine versus other types of pharmacotherapy for depression

LR Magni, M Purgato, C Gastaldon… - Cochrane Database …, 2013 - cochranelibrary.com
Background Depression is common in primary care and is associated with marked personal,
social and economic morbidity, thus creating significant demands on service providers. The …

Issues in treatment-resistant depression

MB Keller - Journal of Clinical Psychiatry, 2005 - psychiatrist.com
Major depressive disorder is a debilitating disease that imposes significant social and
economic burdens not only on patients but also on society. Although various treatment …

Fluoxetine tenth anniversary update: the progress continues

PE Stokes, A Holtz - Clinical therapeutics, 1997 - Elsevier
This tenth anniversary review/update of fluoxetine concentrates on the past 5 years of its
clinical application. The mechanism of action of fluoxetine; its metabolism; its efficacy in …

A review of antidepressant‐induced hypomania in major depression: suggestions for DSM‐V

BJDH Chun, DL Dunner - Bipolar disorders, 2004 - Wiley Online Library
Objectives: To determine if the classification of 'antidepressant‐induced hypomania'in DSM‐
IV is supported by available data. Methods: We reviewed the available scientific literature to …