[HTML][HTML] Multi-Omics Approach to Improved Diagnosis and Treatment of Atopic Dermatitis and Psoriasis

L Rusiñol, L Puig - International Journal of Molecular Sciences, 2024 - mdpi.com
Psoriasis and atopic dermatitis fall within the category of cutaneous immune-mediated
inflammatory diseases (IMIDs). The prevalence of IMIDs is increasing in industrialized …

[HTML][HTML] Functional Genomics and Insights into the Pathogenesis and Treatment of Psoriasis

EM Shellard, SS Rane, S Eyre, RB Warren - Biomolecules, 2024 - mdpi.com
Psoriasis is a lifelong, systemic, immune mediated inflammatory skin condition, affecting 1–
3% of the world's population, with an impact on quality of life similar to diseases like cancer …

[HTML][HTML] Genome-Wide Differential Transcription of Long Noncoding RNAs in Psoriatic Skin

VM Stacey, S Kõks - International journal of molecular sciences, 2023 - mdpi.com
Long noncoding RNAs (lncRNAs) may contribute to the formation of psoriatic lesions. The
present study's objective was to identify long lncRNA genes that are differentially expressed …

[HTML][HTML] A Contemporary, Multifaced Insight into Psoriasis Pathogenesis

RC Dascălu, AL Bărbulescu, LE Stoica… - Journal of Personalized …, 2024 - mdpi.com
Psoriasis is a chronic recurrent inflammatory autoimmune pathology with a significant
genetic component and several interferences of immunological cells and their cytokines …

Evidence for the gut‐skin axis: Common genetic structures in inflammatory bowel disease and psoriasis

J Guo, Q Luo, C Li, H Liang, Q Cao, Z Li… - Skin Research and …, 2024 - Wiley Online Library
Background Inflammatory bowel disease (IBD) and psoriasis (Ps) are common immune‐
mediated diseases that exhibit clinical comorbidity, possibly due to a common genetic …

Genomic Approaches for Drug Repurposing

K Dave, M Sharma, D Patel, PS Dhanda, A Yadav… - 2024 - preprints.org
Functional genomics, a multidisciplinary subject, investigates the functions of genes and
their products in biological systems to better understand diseases and find new drugs. Drug …

[PDF][PDF] Identifying Candidate Biomarkers of Clinical Response to Ustekinumab in Psoriasis

S Solanky - 2024 - kclpure.kcl.ac.uk
The development and use of biologic drugs, including ustekinumab, secukinumab,
adalimumab and newer anti-interleukin (IL)-23p19 biologics, have revolutionised treatment …