Nitric oxide and endothelial dysfunction
AR Cyr, LV Huckaby, SS Shiva… - Critical care …, 2020 - criticalcare.theclinics.com
The vascular endothelium is composed of a monolayer of specialized cells (endothelial
cells), which form the interface between the underlying smooth muscle cells from the …
cells), which form the interface between the underlying smooth muscle cells from the …
Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19
NC Adusumilli, D Zhang, JM Friedman, AJ Friedman - Nitric oxide, 2020 - Elsevier
The ongoing outbreak of COVID-19 has quickly become a daunting challenge to global
health. In the absence of targeted therapy and a reported 5.5% case fatality rate in the …
health. In the absence of targeted therapy and a reported 5.5% case fatality rate in the …
Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection
Background: Since September 2012, 170 confirmed infections with Middle East respiratory
syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization …
syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization …
Management of severe acute respiratory distress syndrome: a primer
JC Grotberg, D Reynolds, BD Kraft - Critical Care, 2023 - Springer
This narrative review explores the physiology and evidence-based management of patients
with severe acute respiratory distress syndrome (ARDS) and refractory hypoxemia, with a …
with severe acute respiratory distress syndrome (ARDS) and refractory hypoxemia, with a …
Diagnostic workup, etiologies and management of acute right ventricle failure: a state-of-the-art paper
A Vieillard-Baron, R Naeije, F Haddad… - Intensive care …, 2018 - Springer
Introduction This is a state-of-the-art article of the diagnostic process, etiologies and
management of acute right ventricular (RV) failure in critically ill patients. It is based on a …
management of acute right ventricular (RV) failure in critically ill patients. It is based on a …
Small studies may overestimate the effect sizes in critical care meta-analyses: a meta-epidemiological study
Z Zhang, X Xu, H Ni - Critical Care, 2013 - Springer
Introduction Small-study effects refer to the fact that trials with limited sample sizes are more
likely to report larger beneficial effects than large trials. However, this has never been …
likely to report larger beneficial effects than large trials. However, this has never been …
Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis
NKJ Adhikari, RP Dellinger, S Lundin… - Critical care …, 2014 - journals.lww.com
Objective: Treatment with inhaled nitric oxide improves oxygenation but not survival in
mechanically ventilated patients with acute respiratory distress syndrome, but the effect may …
mechanically ventilated patients with acute respiratory distress syndrome, but the effect may …
Ferritin-based drug delivery systems: Hybrid nanocarriers for vascular immunotargeting
M Khoshnejad, H Parhiz, VV Shuvaev… - Journal of Controlled …, 2018 - Elsevier
Ferritin subunits of heavy and light polypeptide chains self-assemble into a spherical
nanocage that serves as a natural transport vehicle for metals but can include diverse …
nanocage that serves as a natural transport vehicle for metals but can include diverse …
Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses
AR Tonelli, J Zein, J Adams, JPA Ioannidis - Intensive care medicine, 2014 - Springer
Purpose Multiple interventions have been tested in acute respiratory distress syndrome
(ARDS). We examined the entire agenda of published randomized controlled trials (RCTs) …
(ARDS). We examined the entire agenda of published randomized controlled trials (RCTs) …
Acute respiratory distress syndrome in the perioperative period of cardiac surgery: predictors, diagnosis, prognosis, management options, and future directions
F Sanfilippo, GJ Palumbo, E Bignami, M Pavesi… - Journal of cardiothoracic …, 2022 - Elsevier
Acute respiratory distress syndrome (ARDS) after cardiac surgery is reported with a widely
variable incidence (from 0.4%-8.1%). Cardiac surgery patients usually are affected by …
variable incidence (from 0.4%-8.1%). Cardiac surgery patients usually are affected by …