Sodium-glucose co-transporter 2 (SGLT2) inhibitors block glucose reabsorption in the renal
proximal tubule, an insulin-independent mechanism that plays a critical role in glycemic …

Abstract Type 2 diabetes (T2D) in the East Asian population is characterized by phenotypes
such as low body mass index, an index of β‐cell dysfunction, and higher percentage of body …

Aim To explore the safety and effectiveness of extended exposure to bexagliflozin as a
monotherapy for type 2 diabetes. Methods Adults with diabetes (n= 288) from the USA …

Abstract The Japan Diabetes Society (JDS) adopted a sweeping decision to release
consensus statements on relevant issues in diabetes management that require updating …

Objective To evaluate the long-term safety and effectiveness of ipragliflozin in real-world
clinical practice in Japanese patients with type 2 diabetes mellitus (T2DM). Research design …

Background: Cardiovascular morbidity and mortality are a major burden in patients with type
2 diabetic mellitus. In a landmark study, semaglutide (an injectable glucagon like peptide-1 …

Step-wise addition of antihyperglycemic agents (AHA) after the initiation of metformin
monotherapy has been the traditional approach for the treatment of type 2 diabetes mellitus …

Background: Acarbose and dipeptidyl peptidase-4 inhibitors (DPP-4is) have several
similarities regarding their efficacy. Assessing the hypoglycemic and weight-loss effects, as …

The Japan Diabetes Society (JDS) adopted a sweeping decision to release consensus
statements on relevant issues in diabetes management that require updating from time to …

Objectives To quantify patients' maximum acceptable risk (MAR) of urinary and genital tract
infections (UGTI) in exchange for benefits associated with treatments for managing type 2 …