Frog skin innate immune defences: sensing and surviving pathogens

JFA Varga, MP Bui-Marinos… - Frontiers in …, 2019 - frontiersin.org
Amphibian skin is a mucosal surface in direct and continuous contact with a microbially
diverse and laden aquatic and/or terrestrial environment. As such, frog skin is an important …

Antimicrobial peptides (AMPs): a patent review (2015–2020)

G Annunziato, G Costantino - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
Introduction: Antimicrobial peptides are a large class of compounds that are part of innate
immune response found among all classes of life and are considered promising compounds …

Rediscovery of antimicrobial peptides as therapeutic agents

M Ryu, J Park, JH Yeom, M Joo, K Lee - Journal of Microbiology, 2021 - Springer
In recent years, the occurrence of antibiotic-resistant pathogens is increasing rapidly. There
is growing concern as the development of antibiotics is slower than the increase in the …

[HTML][HTML] Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents

B Mendes, JR Almeida, N Vale, P Gomes… - … and Physiology Part C …, 2019 - Elsevier
Phospholipase A 2 toxins present in snake venoms interact with biological membranes and
serve as structural models for the design of small peptides with anticancer, antibacterial and …

Of poisons and parasites—the defensive role of tetrodotoxin against infections in newts

PTJ Johnson, DM Calhoun, AN Stokes… - Journal of Animal …, 2018 - Wiley Online Library
Classical research on animal toxicity has focused on the role of toxins in protection against
predators, but recent studies suggest these same compounds can offer a powerful defense …

Life history linked to immune investment in developing amphibians

DC Woodhams, SC Bell, L Bigler… - Conservation …, 2016 - academic.oup.com
The broad diversity of amphibian developmental strategies has been shaped, in part, by
pathogen pressure, yet trade-offs between the rate of larval development and immune …

Host-associated helminth diversity and microbiome composition contribute to anti-pathogen defences in tropical frogs impacted by forest fragmentation

WJ Neely, KMC Souza, RA Martins… - Royal Society …, 2024 - royalsocietypublishing.org
Habitat fragmentation can negatively impact wildlife populations by simplification of
ecological interactions, but little is known about how these impacts extend to host …

Antimicrobial peptides from Rana [Lithobates] catesbeiana: Gene structure and bioinformatic identification of novel forms from tadpoles

CC Helbing, SA Hammond, SH Jackman, S Houston… - Scientific Reports, 2019 - nature.com
Antimicrobial peptides (AMPs) exhibit broad-spectrum antimicrobial activity, and have
promise as new therapeutic agents. While the adult North American bullfrog (Rana …

Endocrine and immune responses of larval amphibians to trematode exposure

J Koprivnikar, BJ Hoye, TMY Urichuk… - Parasitology research, 2019 - Springer
In nature, multiple waves of exposure to the same parasite are likely, making it important to
understand how initial exposure or infection affects subsequent host infections, including the …

Anurans against SARS-CoV-2: A review of the potential antiviral action of anurans cutaneous peptides

M de Amaral, J Ienes-Lima - Virus Research, 2022 - Elsevier
At the end of 2019, in China, clinical signs and symptoms of unknown etiology have been
reported in several patients whose sample sequencing revealed pneumonia caused by the …