Influence of cytokine gene polymorphisms on proinflammatory/anti-inflammatory cytokine imbalance in premature coronary artery disease

WM Ansari, SE Humphries, AK Naveed… - Postgraduate …, 2017 - academic.oup.com
Background Genetic information has the potential to create a more personalised, prompt,
early and accurate risk evaluation. The effect of these genetic variants on the serum …

IL1β, IL18, NFKB1 and IFNG gene interactions are associated with severity of rheumatoid arthritis: A pilot study

IIF Gomes da Silva, CAD Lima, MLA Monteiro… - …, 2020 - Taylor & Francis
Rheumatoid arthritis (RA) is an autoimmune disease which can lead to progressive and
functional disability. Literature data suggest that some inflammatory proteins are …

Interleukin-18 gene polymorphism and risk of CVD in older patients with type 2 diabetes mellitus

M Buraczynska, K Ksiazek, P Zukowski… - Diabetes research and …, 2016 - Elsevier
Abstract Objective Interleukin-18 (IL-18), a proinflammatory cytokine, plays a key role in the
acute and chronic inflammatory processes. It is associated with risk of developing …

Efficacy and safety of loading-dose rosuvastatin therapy in elderly patients with acute coronary syndromes undergoing elective percutaneous coronary intervention

Y Jiao, F Hu, Z Zhang, K Gong, X Sun, A Li… - Clinical Drug …, 2015 - Springer
Objectives The aim of this work was to investigate the efficacy and safety of loading-dose
rosuvastatin therapy in elderly patients with non-ST-segment elevation acute coronary …

Association between polymorphisms in interleukin-18 promoter and risk of coronary artery disease: a meta-analysis

Z Lian, SF Li, YX Cui, MY Wu, LN Su, D Hu… - Bioscience …, 2019 - portlandpress.com
Background: Previous studies have explored associations between interleukin-18 (IL-18)
promoter polymorphisms and coronary artery disease (CAD). However, the results were …

Role of cytokine gene score in risk prediction of premature coronary artery disease

W Omer, AK Naveed, OJ Khan… - Genetic Testing and …, 2016 - liebertpub.com
Aims: Pro-and anti-inflammatory cytokines play a significant role in early atherosclerosis.
Linkage disequilibrium patterns differ between ethnic groups pointing toward the need to …

[HTML][HTML] Effect of rosuvastatin dose-loading on serum sLox-1, hs-CRP, and postoperative prognosis in diabetic patients with acute coronary syndromes undergoing …

Y Jiao, F Hu, Z Zhang, K Gong, X Sun… - International journal of …, 2015 - ncbi.nlm.nih.gov
Objective: To investigate the effect of rosuvastatin dose-loading on serum levels of lectin-like
oxidized low-density lipoprotein receptor-1 (Lox-1) and high-sensitivity c-reactive protein (hs …

[HTML][HTML] Association of IL-18 gene polymorphisms with clinical aspects of hyperlipidemia in middle-aged and early people in the community

PC Chen, WH Chen, LM Lien, CC Chou… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Hyperlipidemia is notorious for causing coronary artery disease (CAD). IL-18 is a
proinflammtory cytokine that contributes to the pathogenesis of CAD. Previous reports have …

No association between interleukin-18 levels and risk of cardiovascular disease: a Mendelian randomization study

S Fan, P He, J Guan, W Song, H Zhi, L Wang - Hereditas, 2020 - Springer
Abstract Objective In this study, Mendelian randomization method was used to determine
whether there was a causal association between inflammatory cytokine IL-18 and …

Genetic polymorphisms of eNOS (-786T/C, Intron 4b/4a & 894G/T) and its association with asymptomatic first degree relatives of coronary heart disease patients

GR Kumar, KM Spurthi, GK Kumar, TM Aiyengar… - Nitric Oxide, 2016 - Elsevier
Background The eNOS gene has been extensively screened for important variations in the
promoter (-786T/C), Intron 4 (4b/4a) and exon 7 (894G/T) regions in multiple diseases …