Transcriptional regulation of autophagy and its implications in human disease
Y Lei, DJ Klionsky - Cell Death & Differentiation, 2023 - nature.com
Macroautophagy/autophagy is a conserved catabolic pathway that is vital for maintaining
cell homeostasis and promoting cell survival under stressful conditions. Dysregulation of …
cell homeostasis and promoting cell survival under stressful conditions. Dysregulation of …
Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis
Background Existing meta-analyses on omega-3 polyunsaturated fatty acids and their anti-
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …
The genetic basis of childhood obesity: A systematic review
A Vourdoumpa, G Paltoglou, E Charmandari - Nutrients, 2023 - mdpi.com
Overweight and obesity in childhood and adolescence represents one of the most
challenging public health problems of our century owing to its epidemic proportions and the …
challenging public health problems of our century owing to its epidemic proportions and the …
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection
Abstract Th17-polarized CD4+ effector T-cells together with their immunosuppressive
regulatory T-cell (Treg) counterparts, with transcriptional profiles governed by the lineage …
regulatory T-cell (Treg) counterparts, with transcriptional profiles governed by the lineage …
The global perspective on peroxisome proliferator-activated receptor γ (PPARγ) in ectopic fat deposition: A review
Y Qiu, M Gan, X Wang, T Liao, Q Chen, Y Lei… - International journal of …, 2023 - Elsevier
Excessive expansion of adipocytes can have unhealthy consequences as excess free fatty
acids enter other tissues and cause ectopic fat deposition by resynthesizing triglycerides …
acids enter other tissues and cause ectopic fat deposition by resynthesizing triglycerides …
Fatty acids as potent modulators of autophagy activity in white adipose tissue
K Ciesielska, M Gajewska - Biomolecules, 2023 - mdpi.com
A high-fat diet is one of the causative factors of obesity. The dietary profile of fatty acids is
also an important variable in developing obesity, as saturated fatty acids are more …
also an important variable in developing obesity, as saturated fatty acids are more …
Link between obesity and atopic dermatitis: Does obesity predispose to atopic dermatitis, or vice versa?
S Yang, T Zhu, JS Wakefield, TM Mauro… - Experimental …, 2023 - Wiley Online Library
Two serious health conditions, obesity and atopic dermatitis (AD), share some pathological
features such as insulin resistance, leptin resistance and inflammation, and a growing body …
features such as insulin resistance, leptin resistance and inflammation, and a growing body …
Effect of lipid-lowering therapies on C-reactive protein levels: a comprehensive meta-analysis of randomized controlled trials
Chronic low-degree inflammation is a hallmark of atherosclerotic cardiovascular (CV)
disease. To assess the effect of lipid-lowering therapies on C-reactive protein (CRP), a …
disease. To assess the effect of lipid-lowering therapies on C-reactive protein (CRP), a …
Efficacy of curcumin plus piperine co‐supplementation in moderate‐to‐high hepatic steatosis: a double‐blind, randomized, placebo‐controlled clinical trial
S Sharifi, M Bagherniya, Z Khoram… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Non‐alcoholic Fatty Liver Disease (NAFLD) is a global health problem that can
progress to steatohepatitis and cirrhosis. The aim of this study was to determine the effect of …
progress to steatohepatitis and cirrhosis. The aim of this study was to determine the effect of …
Integrated multi-omics analyses reveal effects of empagliflozin on intestinal homeostasis in high-fat-diet mice
J Shi, H Qiu, Q Xu, Y Ma, T Ye, Z Kuang, N Qu, C Kan… - Iscience, 2023 - cell.com
Obesity has become a global epidemic, associated with several chronic complications. The
intestinal microbiome is a critical regulator of metabolic homeostasis and obesity …
intestinal microbiome is a critical regulator of metabolic homeostasis and obesity …