Virus-based immunotherapy of glioblastoma

M Martikainen, M Essand - Cancers, 2019 - mdpi.com
Glioblastoma (GBM) is the most common type of primary brain tumor in adults. Despite
recent advances in cancer therapy, including the breakthrough of immunotherapy, the …

Non-coding RNAs in glioma

R Rynkeviciene, J Simiene, E Strainiene… - Cancers, 2018 - mdpi.com
Glioma is the most aggressive brain tumor of the central nervous system. The ability of
glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained …

miR-203 inhibits ovarian tumor metastasis by targeting BIRC5 and attenuating the TGFβ pathway

B Wang, X Li, G Zhao, H Yan, P Dong, H Watari… - Journal of Experimental …, 2018 - Springer
Background We previously reported that miR-203 functions as a tumor suppressor in
ovarian cancer cells by directly targeting transcription factor Snai2 and inhibiting epithelial to …

MALAT1-miRNAs network regulate thymidylate synthase and affect 5FU-based chemotherapy

J Matuszyk - Molecular Medicine, 2022 - Springer
Background The active metabolite of 5-Fluorouracil (5FU), used in the treatment of several
types of cancer, acts by inhibiting the thymidylate synthase encoded by the TYMS gene …

miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response

P Biswal, A Lalruatfela, SK Behera, S Biswal… - IUBMB …, 2024 - Wiley Online Library
MicroRNAs (miRNAs) are a class of noncoding RNAs of about 19–25 nucleotides, which
serve as critical modulators of various cellular and biological processes by target gene …

[PDF][PDF] Gieleci nska

M Kciuk, M Malinowska - Molecules, 2023 - pdfs.semanticscholar.org
Multicomponent reactions have emerged as an important approach for the synthesis of
diverse and complicated chemical compounds. They have various advantages over two …

Insights into the role of LncRNAs and miRNAs in glioma progression and their potential as novel therapeutic targets

M Kciuk, EB Yahya, MMI Mohamed, MA Abdulsamad… - Cancers, 2023 - mdpi.com
Simple Summary Recent research has revealed the involvement of long non-coding RNAs
(lncRNAs) and micro RNAs (miRNAs) in glioma development and advancement, suggesting …

MiR-203a-3p regulates the biological behaviors of ovarian cancer cells through mediating the Akt/GSK-3β/Snail signaling pathway by targeting ATM

HY Liu, YY Zhang, BL Zhu, FZ Feng, HT Zhang… - Journal of ovarian …, 2019 - Springer
Objective To investigate whether miR-203a-3p can regulate the biological behaviors of
ovarian cancer cells by targeting ATM to affect the Akt/GSK-3β/Snail signaling pathway …

SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo

Y Wang, C Yang, MM Sims, JR Sacher, M Raje… - Cancer Letters, 2022 - Elsevier
Glioblastoma (GBM) is a highly aggressive cancer with a dismal prognosis. Constitutively
active STAT3 has a causal role in GBM progression and is associated with poor patient …

MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin

CH Yang, Y Wang, M Sims, C Cai, LM Pfeffer - Cancer letters, 2019 - Elsevier
Glioblastoma (GBM) is a deadly and incurable brain tumor. Although microRNAs (miRNAs)
play critical roles in regulating the cancer cell phenotype, the underlying mechanisms of how …