In vitro and in vivo toxicity of pristine C60 fullerene aqueous colloid solution

SV Prylutska, AG Grebinyk, OV Lynchak… - Fullerenes …, 2019 - Taylor & Francis
Toxicity of the C60 fullerene aqueous colloid solution in vitro and in vivo experiments was
studied. C60 fullerene in the concentration range of 3.6–144 µg/mL demonstrated low …

C60 Fullerene as Synergistic Agent in Tumor-Inhibitory Doxorubicin Treatment

S Prylutska, I Grynyuk, O Matyshevska, Y Prylutskyy… - Drugs in R&D, 2014 - Springer
Abstract Background Doxorubicin (Dox) is one of the most potent anticancer drugs, but its
successful use is hampered by high toxicity caused mainly by generation of reactive oxygen …

C60 Fullerenes Diminish Muscle Fatigue in Rats Comparable to N-acetylcysteine or β-Alanine

IV Vereshchaka, NV Bulgakova… - Frontiers in …, 2018 - frontiersin.org
The aim of this study is to detect the effects of C60 fullerenes, which possess pronounced
antioxidant properties, in comparison with the actions of the known exogenous antioxidants …

Analysis of biomechanical parameters of muscle soleus contraction and blood biochemical parameters in rat with chronic glyphosate intoxication and therapeutic use …

D Nozdrenko, O Abramchuk, S Prylutska… - International journal of …, 2021 - mdpi.com
The widespread use of glyphosate as a herbicide in agriculture can lead to the presence of
its residues and metabolites in food for human consumption and thus pose a threat to …

A nanocomplex of C60 fullerene with cisplatin: design, characterization and toxicity

S Prylutska, S Politenkova… - Beilstein journal of …, 2017 - beilstein-journals.org
The self-organization of C 60 fullerene and cisplatin in aqueous solution was investigated
using the computer simulation, dynamic light scattering and atomic force microscopy …

Characterization of C 60 fullerene complexation with antibiotic doxorubicin

YI Prylutskyy, MP Evstigneev, IS Pashkova… - Physical Chemistry …, 2014 - pubs.rsc.org
The aim of this paper was to provide the physico-chemical characterization of a key process
leading to amplification of the antitumor effect of antibiotic Doxorubicin (Dox) in vivo and in …

Structural organization of C60 fullerene, doxorubicin, and their complex in physiological solution as promising antitumor agents

YI Prylutskyy, MP Evstigneev, VV Cherepanov… - Journal of Nanoparticle …, 2015 - Springer
Specific features of structural self-organization of C 60 fullerene (1 nm size range), antitumor
antibiotic doxorubicin (Dox) and their complex in physiological solution (0.9% NaCl) have …

Does C60 fullerene act as a transporter of small aromatic molecules?

A Borowik, Y Prylutskyy, Ł Kawelski, O Kyzyma… - Colloids and Surfaces B …, 2018 - Elsevier
C 60 fullerene is reported to directly interact with biomolecules, such as aromatic mutagens
or anticancer drugs. Therefore, it is extensively studied for its potential application in the …

Toxicity of C60 fullerene–cisplatin nanocomplex against Lewis lung carcinoma cells

S Prylutska, I Grynyuk, T Skaterna, I Horak… - Archives of …, 2019 - Springer
Abstract Cisplatin (Cis-Pt) is the cytotoxic agent widely used against tumors of various origin,
but its therapeutic efficiency is substantially limited by a non-selective effect and high toxicity …

The effect of C60 fullerene on the mechanokinetics of muscle gastrocnemius contraction in chronically alcoholized rats

O Motuziuk, D Nozdrenko, S Prylutska, I Vareniuk… - Heliyon, 2023 - cell.com
The C 60 fullerene effect (oral administration at a dose of 1 mg kg− 1) on the selected
biomechanical parameters of muscle gastrocnemius contraction, biochemical indicators of …