Palmitoylethanolamide (PEA, N-hexadecanoylethanolamide) is an endogenous compound
belonging to the family of N-acylethanolamines. PEA has anti-inflammatory and analgesic …

Introduction The present paper focuses on the possible contribution of food compounds to
alleviate symptomatic pains. Chronic pain can more easily be linked to anticipatory signals …

Chronic pain has a debilitating consequences on health and lifestyle. The currently
available analgesics are often ineffective and accompanied by undesirable adverse effects …

Growing evidence indicates cannabinoid receptors as potential therapeutic targets for
chronic pain. Consequently, there is an increasing interest in developing cannabinoid …

Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory
nervous system and affects 7–10% of the worldwide population. Neuropathic pain can be …

Chemotherapy-induced peripheral neuropathy (CIPN) is a significant adverse effect of many
anticancer drugs. Current strategies for the management of CIPN pain are still largely unmet …

Chronic pain is a persistent and debilitating health problem. Although the use of analgesics
such as opioids is useful in mitigating pain, their prolonged use is associated with unwanted …

Neuropathic pain is a growing healthcare problem causing a global burden. Currently used
analgesics such as opioids are associated with adverse effects; urging the need for safer …

Arbutus andrachne L. is a medicinal plant that grows in Jordan and has many valuable
effects. In the present study, the anti-nociceptive effect of A. andrachne methanolic leaf …

Osteoarthritis (OA) is characterized by cartilage degeneration, subchondral sclerosis, and
pain. Cannabinoids have well-established anti-nociceptive properties in animal models of …