Intracellular organelles are subsystems within a cell, whose activity and chemical
composition reflect the metabolic state of live cells. Alterations in cellular homeostasis …

Cardiovascular diseases (CVDs) are the leading cause of death globally. An effective
strategy to mitigate the burden of CVDs has been to monitor patients' biomedical variables …

High mortality rates due to cardiovascular diseases (CVDs) have attracted worldwide
attention. It has been reported that mitochondrial dysfunction is one of the most important …

Cardiac hypertrophy is an important characteristic in the development of hypertensive heart
disease. Mitochondrial dysfunction plays an important role in the pathology of cardiac …

Herein we trace links between biochemical pathways, pathogenesis, and metabolic
diseases to set the stage for new therapeutic advances. Cellular and acellular …

Preeclampsia, new onset hypertension in pregnancy, affects~ 5%–10% of the world's
population. Preeclampsia is the leading cause of morbidity and mortality for both the mother …

Mitochondrial dysfunction is a key pathological event in many diseases. Its role in energy
production, calcium homeostasis, apoptosis regulation, and reactive oxygen species (ROS) …

Ageing is a crucial risk factor for the development of age‐related cardiovascular diseases.
Therefore, the molecular mechanisms of ageing and novel anti‐ageing interventions need to …

Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related
death worldwide, and effective therapeutic strategies against CVD are urgently needed …

Sodium-glucose cotransporter 2 inhibitors (SGLT2is) are a class of newly introduced
antidiabetic drugs with potent hypoglycemic effects. Recent evidence suggests that these …