New insights into natural products that target the gut microbiota: Effects on the prevention and treatment of colorectal cancer

L Lu, J Dong, Y Liu, Y Qian, G Zhang, W Zhou… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

Colon carcinogenesis: the interplay between diet and gut microbiota

YL Loke, MT Chew, YF Ngeow, WWD Lim… - Frontiers in cellular and …, 2020 - frontiersin.org
Colorectal cancer (CRC) incidence increases yearly, and is three to four times higher in
developed countries compared to developing countries. The well-known risk factors have …

Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase

Q Li, W Hu, WX Liu, LY Zhao, D Huang, XD Liu… - Gastroenterology, 2021 - Elsevier
Background & Aims Streptococcus thermophilus was identified to be depleted in patients
with colorectal cancer (CRC) by shotgun metagenomic sequencing of 526 multicohort fecal …

Alterations in the gut microbiota and their metabolites in colorectal cancer: recent progress and future prospects

J Li, A Zhang, F Wu, X Wang - Frontiers in Oncology, 2022 - frontiersin.org
Colorectal cancer (CRC) is a leading cause of cancer morbidity and mortality worldwide.
The etiology and pathogenesis of CRC remain unclear. A growing body of evidence …

Therapeutic strategies targeting Wnt/β‑catenin signaling for colorectal cancer

Y Ji, J Lv, D Sun, Y Huang - … journal of molecular …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice

G Ding, Q Gong, J Ma, X Liu, Y Wang… - Cancer science, 2021 - Wiley Online Library
Astragalus polysaccharides (APS), the main effective component of Astragalus
membranaceus, can inhibit tumor growth, but the underlying mechanisms remain unclear …

Therapeutic approaches to colorectal cancer via strategies based on modulation of gut microbiota

M Chen, W Lin, N Li, Q Wang, S Zhu, A Zeng… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) ranks third in terms of global incidence and second in terms of
death toll among malignant tumors. Gut microbiota are involved in the formation …

Alterations in the oral and gut microbiome of colorectal cancer patients and association with host clinical factors

Y Wang, Y Zhang, Y Qian, YH Xie… - … journal of cancer, 2021 - Wiley Online Library
Previous studies have suggested that gut microbiota plays a critical role in colorectal cancer
(CRC). Although preliminary comparisons of the oral and gut microbiota between CRC and …

Gut microbiome, metabolome and alopecia areata

Z Liu, X Liu - Frontiers in Microbiology, 2023 - frontiersin.org
Alopecia areata (AA) is a type of dermatological disease characterized by rapid and non-
scarring hair loss of the scalp or body skin that may be related to genetic, immunological and …

The gut microbiota can orchestrate the signaling pathways in colorectal cancer

ALB Bennedsen, S Furbo, T Bjarnsholt, H Raskov… - Apmis, 2022 - Wiley Online Library
Current evidence suggests that bacteria contribute to the development of certain cancers,
such as colorectal cancer (CRC), partly by stimulating chronic inflammation. However, little …