Potentially inappropriate medication in the elderly: a systematic review of validated explicit criteria

FR Motter, JS Fritzen, SN Hilmer, ÉV Paniz… - European journal of …, 2018 - Springer
Purpose Potentially inappropriate medication (PIM) use causes preventable adverse drug
reactions in older patients. Several assessment tools have been published to identify and …

Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review

MS Salahudeen, SB Duffull, PS Nishtala - BMC geriatrics, 2015 - Springer
Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …

Humidity's role in heat-related health outcomes: a heated debate

JW Baldwin, T Benmarhnia, KL Ebi, O Jay… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: As atmospheric greenhouse gas concentrations continue to rise, temperature
and humidity will increase further, causing potentially dire increases in human heat stress …

Anticholinergic drug exposure and the risk of dementia: a nested case-control study

CAC Coupland, T Hill, T Dening, R Morriss… - JAMA internal …, 2019 - jamanetwork.com
Importance Anticholinergic medicines have short-term cognitive adverse effects, but it is
uncertain whether long-term use of these drugs is associated with an increased risk of …

American Geriatrics Society 2015 updated beers criteria for potentially inappropriate medication use in older adults

… 2015 Beers Criteria Update Expert Panel… - Journal of the …, 2015 - Wiley Online Library
The 2015 American Geriatrics Society (AGS) Beers Criteria are presented. Like the 2012
AGS Beers Criteria, they include lists of potentially inappropriate medications to be avoided …

Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study

SL Gray, ML Anderson, S Dublin, JT Hanlon… - JAMA internal …, 2015 - jamanetwork.com
Importance Many medications have anticholinergic effects. In general, anticholinergic-
induced cognitive impairment is considered reversible on discontinuation of anticholinergic …

Anticholinergic drugs in geriatric psychopharmacology

J López-Álvarez, J Sevilla-Llewellyn-Jones… - Frontiers in …, 2019 - frontiersin.org
Drugs with anticholinergic action are widely prescribed in the elderly population due to their
potential clinical benefits. However, these benefits are limited by adverse effects which may …

Anticholinergic drugs and negative outcomes in the older population: from biological plausibility to clinical evidence

A Collamati, AM Martone, A Poscia, V Brandi… - Aging clinical and …, 2016 - Springer
The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

An anticholinergic burden score for German prescribers: score development

EK Kiesel, YM Hopf, M Drey - BMC geriatrics, 2018 - Springer
Background Anticholinergic drugs put elderly patients at a higher risk for falls, cognitive
decline, and delirium as well as peripheral adverse reactions like dry mouth or constipation …

Anticholinergics: theoretical and clinical overview

PS Nishtala, MS Salahudeen… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Anticholinergics are a class of medicines that block the neurotransmitter,
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …