The yeast deletion collection: a decade of functional genomics
The yeast deletion collections comprise> 21,000 mutant strains that carry precise start-to-
stop deletions of∼ 6000 open reading frames. This collection includes heterozygous and …
stop deletions of∼ 6000 open reading frames. This collection includes heterozygous and …
Recent advances in synthetic biology for engineering isoprenoid production in yeast
Highlights•Isoprenoids are industrially important natural products.•Yeast are key industrial
production vehicles.•New synthetic biology approaches in recent years are reviewed.•Future …
production vehicles.•New synthetic biology approaches in recent years are reviewed.•Future …
Yeast creates a niche for symbiotic lactic acid bacteria through nitrogen overflow
Many microorganisms live in communities and depend on metabolites secreted by fellow
community members for survival. Yet our knowledge of interspecies metabolic …
community members for survival. Yet our knowledge of interspecies metabolic …
Cysteine toxicity drives age-related mitochondrial decline by altering iron homeostasis
Mitochondria and lysosomes are functionally linked, and their interdependent decline is a
hallmark of aging and disease. Despite the long-standing connection between these …
hallmark of aging and disease. Despite the long-standing connection between these …
Spontaneously established syntrophic yeast communities improve bioproduction
Nutritional codependence (syntrophy) has underexplored potential to improve
biotechnological processes by using cooperating cell types. So far, design of yeast …
biotechnological processes by using cooperating cell types. So far, design of yeast …
Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC
S Kamrad, C Correia-Melo, L Szyrwiel, SK Aulakh… - Nature …, 2023 - nature.com
Genetically identical cells are known to differ in many physiological parameters such as
growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such …
growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such …
Cytosine DNA Methylation Is Found in Drosophila melanogaster but Absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and Other Yeast Species
F Capuano, M Mülleder, R Kok, HJ Blom… - Analytical …, 2014 - ACS Publications
The methylation of cytosine to 5-methylcytosine (5-meC) is an important epigenetic DNA
modification in many bacteria, plants, and mammals, but its relevance for important model …
modification in many bacteria, plants, and mammals, but its relevance for important model …
Global analysis of the yeast knockout phenome
Genome-wide phenotypic screens in the budding yeast Saccharomyces cerevisiae, enabled
by its knockout collection, have produced the largest, richest, and most systematic …
by its knockout collection, have produced the largest, richest, and most systematic …
The proteomic landscape of genome-wide genetic perturbations
Functional genomic strategies have become fundamental for annotating gene function and
regulatory networks. Here, we combined functional genomics with proteomics by quantifying …
regulatory networks. Here, we combined functional genomics with proteomics by quantifying …
The fascinating and secret wild life of the budding yeast S. cerevisiae
G Liti - Elife, 2015 - elifesciences.org
The budding yeast Saccharomyces cerevisiae has been used in laboratory experiments for
over a century and has been instrumental in understanding virtually every aspect of …
over a century and has been instrumental in understanding virtually every aspect of …