Nanomaterials are promising carriers to improve the bioavailability and therapeutic
efficiency of drugs by providing preferential drug accumulation at their sites of action, but …

Red blood cell (RBC) hitchhiking is a method of drug delivery that can increase drug
concentration in target organs by orders of magnitude. In RBC hitchhiking, drug-loaded …

Drug delivery research pursues many types of carriers including proteins and other
macromolecules, natural and synthetic polymeric structures, nanocarriers of diverse …

Abstract Alternatively-activated, M2-like tumor-associated macrophages (TAM) strongly
contribute to tumor growth, invasiveness and metastasis. Technologies to disable the pro …

Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
developing field. Such erythrocytes can act as carriers that prolong the drug's action due to …

Myeloid cells are the most abundant cells in the tumor microenvironment (TME). The tumor
recruits and modulates endogenous myeloid cells to tumor-associated macrophages (TAM) …

In recent years, the influence of the tumor microenvironment (TME) on cancer progression
has been better understood. Macrophages, one of the most important cell types in the TME …

Acute pneumonia is an inflammatory syndrome often associated with severe multi-organ
dysfunction and high mortality. The therapeutic efficacy of current anti-inflammatory …

Radiotherapy (IR) is capable of enhancing antitumor immune responses. However, IR
treatment also aggravates the infiltration of peripheral macrophages into the tumor, resulting …

The relationship between obesity and breast cancer (BC) has focused on serum factors.
However, the mammary gland contains adipose tissue (AT) which may enable the crosstalk …