Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance

MKM Herzog, M Cazzaniga, A Peters, N Shayya… - Gut …, 2023 - Taylor & Francis
Globally, enteropathogenic bacteria are a major cause of morbidity and mortality. 1-3
Campylobacter, Salmonella, Shiga-toxin-producing Escherichia coli, and Listeria are among …

Clostridioides difficile, a New “Superbug”

R Markovska, G Dimitrov, R Gergova, L Boyanova - Microorganisms, 2023 - mdpi.com
Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical
features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and …

Inhibition of In Vitro Clostridioides difficile Biofilm Formation by the Probiotic Yeast Saccharomyces boulardii CNCM I-745 through Modification of the Extracellular …

PA Lacotte, A Simons, S Bouttier, J Malet-Villemagne… - Microorganisms, 2022 - mdpi.com
Clostridioides difficile is responsible for post-antibiotic diarrhea and most of the
pseudomembranous colitis cases. Multiple recurrences, one of the major challenges faced …

[HTML][HTML] Clostridioides difficile infection-associated cause-specific and all-cause mortality: a population-based cohort study

A Boven, E Vlieghe, L Engstrand, FL Andersson… - Clinical Microbiology …, 2023 - Elsevier
Objectives Clostridioides difficile infection (CDI) is a common healthcare-associated
infection and leading cause of gastroenteritis-related mortality worldwide. However, data on …

Wolf in Sheep's Clothing: Clostridioides difficile Biofilm as a Reservoir for Recurrent Infections

J Meza-Torres, E Auria, B Dupuy, YDN Tremblay - Microorganisms, 2021 - mdpi.com
The microbiota inhabiting the intestinal tract provide several critical functions to its host.
Microorganisms found at the mucosal layer form organized three-dimensional structures …

Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?

K Fettucciari, A Fruganti, F Stracci, A Spaterna… - International Journal of …, 2023 - mdpi.com
Clostridioides difficile (C. difficile) is responsible for a high percentage of gastrointestinal
infections and its pathological activity is due to toxins A and BC difficile infection (CDI) is …

Emerging antimicrobial resistance

CE Flynn, J Guarner - Modern Pathology, 2023 - Elsevier
The burden of emerging antimicrobial resistance (AMR) in the United States is significant
and even greater worldwide. Mitigation efforts have decreased the incidence and deaths …

[HTML][HTML] Trends in and risk factors for recurrent Clostridioides difficile infection, New Haven County, Connecticut, USA, 2015–2020

CM Okafor, P Clogher, D Olson, L Niccolai… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Recurrent Clostridioides difficile infection (RCDI) causes an increased burden on the
healthcare system. We calculated RCDI incidence and identified factors associated with …

The roles of the virome in cancer

F Broecker, K Moelling - Microorganisms, 2021 - mdpi.com
Viral infections as well as changes in the composition of the intestinal microbiota and virome
have been linked to cancer. Moreover, the success of cancer immunotherapy with …

Antibiotic-Specific Risk for Community-Acquired Clostridioides difficile Infection in the United States from 2008 to 2020

J Zhang, L Chen, A Gomez-Simmonds… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Antibiotic exposure is a crucial risk factor for community-acquired Clostridioides difficile
infection (CA-CDI). However, the relative risks associated with specific antibiotics may vary …