Purpose Liver diseases are associated with decreased bone mineral density (BMD) and
evidence suggests that nonalcoholic fatty liver disease (NAFLD) affects several extra …

Growing epidemiological evidence connects obesity and its complications, including
metabolic syndrome, diabetes, and nonalcoholic fatty liver disease (NAFLD) to reduced …

Bone defects are common in elderly patients suffering from osteoporosis. Current methods
of bone defect treatment for osteoporosis are not always satisfactory. In this study, we …

Osteopontin (OPN)-deficient mice are resistant to ovariectomy-induced osteoporosis.
Therefore, we hypothesized that women with OPN overexpression may show less resistance …

Alterations in bone tissue composition during osteoporosis likely disrupt the mechanical
environment of bone cells and may thereby initiate a mechanobiological response. It has …

Abstract Purpose of the Review This review summarizes research on the use of sheep and
goats as large animal models of human osteoporosis for preclinical and translational …

Milk contains various bioactive components with osteoanabolic properties. This study
investigates the comparative effect of the whey-derived antioxidative (YVEEL) and …

Recent studies suggest that osteopontin (OPN) could be used as an early marker for the
diagnosis of bone disorders. Considering the contradictory opinions in the literature, the …

Experimental studies have shown that primary osteoporosis caused by oestrogen-deficiency
results in localised alterations in bone tissue properties and mineral composition …

Osteoporosis and treatment may affect both composition and nanomechanical properties
and their spatial distributions within the individual trabeculae of cancellous bone at length …