Infection after fracture fixation: current surgical and microbiological concepts

WJ Metsemakers, R Kuehl, TF Moriarty, RG Richards… - Injury, 2018 - Elsevier
One of the most challenging complications in trauma surgery is infection after fracture
fixation (IAFF). IAFF may result in permanent functional loss or even amputation of the …

Staphylococcus aureus osteomyelitis: bone, bugs, and surgery

KL Urish, JE Cassat - Infection and immunity, 2020 - Am Soc Microbiol
Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial
pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part …

Guidelines on the diagnosis and treatment of foot infection in persons with diabetes (IWGDF 2019 update)

BA Lipsky, É Senneville, ZG Abbas… - Diabetes/metabolism …, 2020 - Wiley Online Library
Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections

BA Lipsky, AR Berendt, PB Cornia… - Clinical infectious …, 2012 - academic.oup.com
Foot infections are a common and serious problem in persons with diabetes. Diabetic foot
infections (DFIs) typically begin in a wound, most often a neuropathic ulceration. While all …

Biomaterials approaches to treating implant-associated osteomyelitis

JA Inzana, EM Schwarz, SL Kates, HA Awad - Biomaterials, 2016 - Elsevier
Orthopaedic devices are the most common surgical devices associated with implant-related
infections and Staphylococcus aureus (S. aureus) is the most common causative pathogen …

[HTML][HTML] Pathogenesis and management of fracture-related infection

M Depypere, M Morgenstern, R Kuehl… - Clinical Microbiology …, 2020 - Elsevier
Background Both fracture-related infections (FRIs) and periprosthetic joint infections (PJIs)
include orthopaedic implant-associated infections. However, key aspects of management …

Diagnosis and treatment of diabetic foot infections

BA Lipsky, AR Berendt, HG Deery… - Plastic and …, 2006 - journals.lww.com
1. Foot infections in patients with diabetes cause substantial morbidity and frequent visits to
health care professionals and may lead to amputation of a lower extremity. 2. Diabetic foot …

Treatment for diabetic foot ulcers

PR Cavanagh, BA Lipsky, AW Bradbury, G Botek - The Lancet, 2005 - thelancet.com
People with diabetes develop foot ulcers because of neuropathy (sensory, motor, and
autonomic deficits), ischaemia, or both. The initiating injury may be from acute mechanical or …

Antibiotics for treating chronic osteomyelitis in adults

LO Conterno, MD Turchi - Cochrane database of systematic …, 2013 - cochranelibrary.com
Background Chronic osteomyelitis is generally treated with antibiotics and surgical
debridement but can persist intermittently for years with frequent therapeutic failure or …

Outcome of diabetic foot osteomyelitis treated nonsurgically: a retrospective cohort study

E Senneville, A Lombart, E Beltrand, M Valette… - Diabetes …, 2008 - Am Diabetes Assoc
OBJECTIVE—The purpose of this article was to identify criteria predictive of remission in
nonsurgical treatment of diabetic foot osteomyelitis. RESEARCH DESIGN AND METHODS …