Endogenous toxic metabolites and implications in cancer therapy
N Lee, ME Spears, AE Carlisle, D Kim - Oncogene, 2020 - nature.com
It is well recognized that many metabolic enzymes play essential roles in cancer cells in
producing building blocks such as nucleotides, which are required in greater amounts due …
producing building blocks such as nucleotides, which are required in greater amounts due …
BioTransformer 3.0—a web server for accurately predicting metabolic transformation products
DS Wishart, S Tian, D Allen, E Oler… - Nucleic acids …, 2022 - academic.oup.com
Abstract BioTransformer 3.0 (https://biotransformer. ca) is a freely available web server that
supports accurate, rapid and comprehensive in silico metabolism prediction. It combines …
supports accurate, rapid and comprehensive in silico metabolism prediction. It combines …
Chemical-damage MINE: A database of curated and predicted spontaneous metabolic reactions
Spontaneous reactions between metabolites are often neglected in favor of emphasizing
enzyme-catalyzed chemistry because spontaneous reaction rates are assumed to be …
enzyme-catalyzed chemistry because spontaneous reaction rates are assumed to be …
A Computational Biology Study on the Structure and Dynamics Determinants of Thermal Stability of the Chitosanase from Aspergillus fumigatus
Environmentally friendly and efficient biodegradation with chitosanase for degrading
chitosan to oligosaccharide has been gaining more importance. Here, we studied a …
chitosan to oligosaccharide has been gaining more importance. Here, we studied a …
Efficient Enumeration of Branched Novel Biochemical Pathways Using a Probabilistic Technique
Z Xu, R Mahadevan - Industrial & Engineering Chemistry …, 2022 - ACS Publications
The advancement in the field of synthetic biology has allowed metabolic engineers to
construct de novo pathways in engineered cells. The promiscuous activities of many …
construct de novo pathways in engineered cells. The promiscuous activities of many …