Improving the stability of proteins is an important goal in many biomedical and industrial
applications. A logical approach is to emulate stabilizing molecular interactions found in …

Bioluminescent systems are considered as potent reporter systems for bioanalysis since
they have specific characteristics, such as relatively high quantum yields and photon …

Four fluorescent DNA-stabilized fluorescent silver nanoclusters (DNA–AgNCs) were
designed and synthesized with differences in lengths of cytosine-rich DNA strand (as the …

SpyTag can spontaneously form a covalent isopeptide bond with its protein partner
SpyCatcher. Firefly luciferase from Photinus pyralis was cyclized in vivo by fusing …

Objective: Knowledge regarding interactions of AFB 1 with the human nervous system and
how a naturally occurring level of AFB 1 could potentially induce neuroimmune …

Antibacterial activity of dressings containing antimicrobials is mostly evaluated using in vitro
tests. However, the various methods available differ significantly in their properties and …

The aggregation of alpha-synuclein (αS), natively unstructured presynaptic protein, is a
crucial factor leading to the pathogenesis of Parkinson's disease (PD) and other related …

We present here a novel whole-cell biosensor to detect early-stages of apoptosis based on
Apaf-1 oligomerization and apoptosome formation using the split luciferase strategy. The …

A bioluminescence-based assay for ATP can measure cell viability. Higher ATP
concentration indicates a higher number of living cells. Thus, it is necessary to design an …

In most bioluminescence systems the oxidation of luciferin and production of light is
catalyzed by luciferases. Protein engineering studies have shown that thermostable proteins …