Resistance of solid tumors to chemo‐and radiotherapy remains a major obstacle in anti‐
cancer treatment. Herein, the membrane protein caveolin‐1 (CAV1) came into focus as it is …

Cellular senescence is a feature of most somatic cells. It is characterized by an irreversible
cell cycle arrest and by the ability to secrete a plethora of mediators of inflammation and …

Background Although temozolomide (TMZ) resistance is a significant clinical problem in
glioblastoma (GBM), its underlying molecular mechanisms are poorly understood. In this …

Background Glioblastoma (GBM) stemlike cells (GSCs) are thought to be responsible for the
maintenance and aggressiveness of GBM, the most common primary brain tumor in adults …

Caveolae are specialized plasma membrane subdomains with distinct lipid and protein
compositions, which play an essential role in cell physiology through regulation of trafficking …

Glioblastoma (GBM) is the most common and devastating malignant brain tumor in adults.
The mortality rate is very high despite different treatments. New therapeutic targets are …

Caveolin-1 (CAV1) is a scaffolding protein with a controversial role in cancer. This review
will initially discuss earlier studies focused on the role as a tumor suppressor before …

Glioblastoma (GBM) is one of the most aggressive human cancers with a median survival of
less than two years. A distinguishing pathological feature of GBM is a high degree of inter …

Non-alcoholic fatty liver disease (NAFLD) is the most burgeoning chronic liver disease
worldwide whose pathogenesis is complex and controversial. Here, we investigated the …

Glioblastoma is a particularly resilient cancer, and while therapies may be able to reach the
brain by crossing the blood–brain barrier, they then have to deal with a highly invasive tumor …