There is growing recognition of the critical role of platelets in inflammation and immune
responses. Recent studies have indicated that antiplatelet medications may reduce mortality …

Classically, platelets have been described as the cellular blood component that mediates
hemostasis and thrombosis. This important platelet function has received significant …

The most frequent and feared complication of paroxysmal nocturnal hemoglobinuria (PNH)
is thrombosis. Recent research has demonstrated that the complement and coagulation …

Coagulation and innate immunity are linked evolutionary processes that orchestrate the host
defence against invading pathogens and injury. The complement system is integral to innate …

Inflammation is an underlying feature of a variety of human diseases. An important
manifestation of this pathophysiological response is microvascular dysfunction, which …

Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Platelets have long been known for their role in hemostasis. In this, platelet adhesion and
activation leads to the formation of a firm thrombus and thus the sealing of a damaged blood …

Platelets play an essential role in maintaining homeostasis in the circulatory system after an
injury by forming a platelet thrombus, but they also occupy a central node in the …

Platelets participate in a variety of responses of the blood to injury. An emerging body of
evidence suggests that these cells express an intrinsic capacity to interact with and trigger …

Innate immunity is fundamental to our defense against microorganisms. Physiologically, the
intravascular innate immune system acts as a purging system that identifies and removes …