Current therapies for immune thrombocytopenia (ITP) are successful in providing a
haemostatic platelet count in over two‐thirds of patients. Still, some patients have an …

The effects of a subclass of monoclonal antibodies (mAbs) on protein–protein interactions,
formation of reversible oligomers (clusters), and viscosity (η) are not well understood at high …

Immune thrombocytopenia (ITP) is an autoimmune disorder that causes a significant
reduction in peripheral blood platelet count. Fortunately, due to an increased understanding …

Although incredibly diverse in specificity, millions of unique Immunoglobulin G (IgG)
molecules in the human antibody repertoire share most of their amino acid sequence. These …

Human immunoglobulin G subclass 3 (IgG3) possesses a uniquely long hinge region that
separates its Fab antigen-binding and Fc receptor-binding regions. Owing to this hinge …

We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x
anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of …

Immunoglobulin G (IgG) exhibits potent antiviral, antibacterial, and immunological activities.
The digestion process and bioavailability of IgG are often a concern. Dietary hydrocolloids …

Heavy chain–only antibodies can offer advantages of higher binding affinities, reduced
sizes, and higher stabilities than conventional antibodies. To address the challenge of SARS …

Background This study aimed to investigate the role of anti-CFH autoantibodies in lupus
nephritis based on a well-defined cohort. Methods One hundred twenty patients with biopsy …

The human immunoglobulin G (IgG) class is the most prevalent antibody in serum, with the
IgG1 subclass being the most abundant. IgG1 is composed of two Fab regions connected to …