The measurement of vascular function in isolated vessels has revealed important insights
into the structural, functional, and biomechanical features of the normal and diseased …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

The study of adipose tissue (AT) is enjoying a renaissance. White, brown, and beige
adipocytes are being investigated in adult animals, and the critical roles of small depots like …

The perivascular adipose tissue (PVAT) is an adipose tissue depot which surrounds most
human blood vessels. It is metabolically active and has both a protective and a pathogenic …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

Significance: Perivascular adipose tissue (PVAT), which is present surrounding most blood
vessels, from the aorta to the microvasculature of the dermis, is mainly composed of fat cells …

The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger
widely distributed in the brain and various other organs. Its homeostasis is maintained by the …

Perivascular adipocytes residing in the vascular adventitia are recognized as distinct
endocrine cells capable of responding to inflammatory stimuli and communicating with the …

Transient receptor potential (TRP) channels are not only the major contributors to Ca2+
signaling but also the targets of Ca2+ signaling. Ca2+ regulation of TRP channels involves 3 …

The adipose tissue surrounding blood vessels is known as perivascular adipose tissue
(PVAT), which represents a distinct ectopic fat depot that adheres to the majority of the …