Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Lipid droplets (LDs) are commonly found in various biological cells and are organelles
related to cell metabolism. LDs, the number and size of which are heterogeneous across cell …

Conventional antibiotics used for treating tuberculosis (TB) suffer from drug resistance and
multiple complications. Here we propose a lesion–pathogen dual-targeting strategy for the …

Mycobacterium tuberculosis (Mtb) is the microorganism that causes tuberculosis. This
infectious disease has been around for centuries, with the earliest record of Mtb around …

Cardiac remodeling is the process by which the heart adapts to stressful stimuli, such as
hypertension and ischemia/reperfusion; it ultimately leads to heart failure upon long-term …

Tuberculosis (TB) is currently the second deadliest infectious disease. Existing
antitubercular therapies are long, complex, and have severe side effects that result in low …

Tuberculosis (TB) is a highly contagious bacterial infection caused by Mycobacterium
tuberculosis (Mtb), which has been ranked as the second leading cause of death worldwide …

Being among the top 10 causes of adult deaths, tuberculosis (TB) disease is considered a
major global public health concern to address. The human tuberculosis pathogen …

Autophagy is critically involved in host defense pathways through targeting and elimination
of numerous pathogens via autophagic machinery. Nontuberculous mycobacteria (NTMs) …

Tuberculosis is a major global threat to human health. Since the widely used BCG vaccine is
poorly effective in adults, there is a demand for the development of a new type of boost …