Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

Cancer cells often encounter hypoxic and hypo-nutrient conditions, which force them to
make adaptive changes to meet their high demands for energy and various biomaterials for …

Background & Aims Little is known about the metabolic regulation of cancer stem cells
(CSCs) in cholangiocarcinoma (CCA). We analyzed whether mitochondrial-dependent …

The multiple beneficial effects of the short-chain fatty acid (SCFA) butyrate on human health,
produced from fermentable carbohydrates by gut microbiota in the colon, are well known. At …

Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular
aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of …

Background: Cholangiocarcinoma has obvious primary multidrug resistance and is
generally resistant to cisplatin and other chemotherapy drugs and high glycolytic levels may …

Intrahepatic cholangiocarcinoma (iCCA) is a relatively rare, but highly lethal and biologically
complex primary biliary epithelial cancer arising within liver. After hepatocellular carcinoma …

Simple Summary The reprogramming of tumor cell metabolism is an important char acteristic
of cancer, which provides the energy and biomacromolecules in tumor development …

Cholangiocarcinoma (CCA) is a rare malignancy originating from the biliary tree and is
anatomically categorized as intrahepatic (iCCA), perihilar, and extrahepatic or distal. iCCA …

Introduction: Cholangiocarcinoma (CCA) is a malignancy which arises from the biliary
epithelium. Carcinogenesis of CCA is mainly linked to aberrant glucose metabolism and …