Genetic interactions influencing a phenotype of interest can be identified systematically
using libraries of genetic tools that perturb biological systems in a defined manner …

Accurate and reproducible quantification of the accumulation of proteins into foci in cells is
essential for data interpretation and for biological inferences. To improve reproducibility …

The increasing availability and performance of automated scientific equipment in the past
decades have brought about a revolution in the biological sciences. The ease with which …

Cell cycle progression relies on coordinated changes in the composition and subcellular
localization of the proteome. By applying two distinct convolutional neural networks on …

Saccharomyces cerevisiae, ie baker's yeast, is a widely studied model organism in
eukaryote genetics because of its simple protocols for genetic manipulation and phenotype …

Summary mRNAs encoding polarity and secretion factors (POLs) target the incipient bud site
in yeast for localized translation during division. In pheromone-treated cells we now find that …

Formins associate with other nucleators and nucleation-promoting factors (NPFs) to
stimulate collaborative actin assembly, but the mechanisms regulating these interactions …

Polystyrene latex (PSL) nanoparticles (NPs), 1, 2-dioleoyl-sn-glycero-3-phosphocholine
(DOPC) liposomes, and hybrid NPs that have different concentrations, sizes, surface …

Protein tyrosine nitration (PTN) is a PTM that regulates signal transduction and inflammatory
responses, and is related to neurodegenerative and cardiovascular diseases. The cellular …

Discriminating among diverse environmental stimuli is critical for organisms to ensure their
proper development, homeostasis, and survival. Saccharomyces cerevisiae regulates …