Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

[HTML][HTML] Probing the binding and activation of small molecules by gas-phase transition metal clusters via IR spectroscopy

A Fielicke - Chemical Society Reviews, 2023 - pubs.rsc.org
Isolated transition metal clusters have been established as useful models for extended metal
surfaces or deposited metal particles, to improve the understanding of their surface …

Enhanced optical asymmetry in supramolecular chiroplasmonic assemblies with long-range order

J Lu, Y Xue, K Bernardino, NN Zhang, WR Gomes… - Science, 2021 - science.org
Chiral assemblies of plasmonic nanoparticles are known for strong circular dichroism but not
for high optical asymmetry, which is limited by the unfavorable combination of electrical and …

A hairpin motif in the amyloid-β peptide is important for formation of disease-related oligomers

M Khaled, I Rönnbäck, LL Ilag… - Journal of the …, 2023 - ACS Publications
The amyloid-β (Aβ) peptide is associated with the development of Alzheimer's disease and
is known to form highly neurotoxic prefibrillar oligomeric aggregates, which are difficult to …

[HTML][HTML] Visualizing and trapping transient oligomers in amyloid assembly pathways

EE Cawood, TK Karamanos, AJ Wilson… - Biophysical chemistry, 2021 - Elsevier
Oligomers which form during amyloid fibril assembly are considered to be key contributors
towards amyloid disease. However, understanding how such intermediates form, their …

Charge‐induced secondary structure transformation of amyloid‐derived dipeptide assemblies from β‐sheet to α‐helix

R Xing, C Yuan, S Li, J Song, J Li… - Angewandte Chemie …, 2018 - Wiley Online Library
Secondary structures such as α‐helix and β‐sheet are the major structural motifs within the
three‐dimensional geometry of proteins. Therefore, structure transitions from β‐sheet to α …

Quantitative approach to study secondary structure of proteins by FT-IR spectroscopy, using a model wheat gluten system

M Fevzioglu, OK Ozturk, BR Hamaker… - International Journal of …, 2020 - Elsevier
Abstract Amide I and Amide III vibrational modes are frequently used to study protein
secondary structure with Fourier transform infrared (FT-IR) spectroscopy. However, for …

Porphyrinoids, a unique platform for exploring excited-state aromaticity

J Kim, J Oh, A Osuka, D Kim - Chemical Society Reviews, 2022 - pubs.rsc.org
Recently, Baird (anti) aromaticity has been referred to as a description of excited-state (anti)
aromaticity. With the term of Baird's rule, recent studies have intensively verified that the …

Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria

RS Li, J Liu, C Wen, Y Shi, J Ling, Q Cao, L Wang… - Science …, 2023 - science.org
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …

Adding a new separation dimension to MS and LC–MS: what is the utility of ion mobility spectrometry?

V d'Atri, T Causon, O Hernandez‐Alba… - Journal of separation …, 2018 - Wiley Online Library
Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …