[HTML][HTML] Biofilm matrixome: extracellular components in structured microbial communities

L Karygianni, Z Ren, H Koo, T Thurnheer - Trends in microbiology, 2020 - cell.com
Biofilms consist of microbial communities embedded in a 3D extracellular matrix. The matrix
is composed of a complex array of extracellular polymeric substances (EPS) that contribute …

Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Copper doped carbon dots for addressing bacterial biofilm formation, wound infection, and tooth staining

M Liu, L Huang, X Xu, X Wei, X Yang, X Li, B Wang… - ACS …, 2022 - ACS Publications
Oral infectious diseases and tooth staining, the main challenges of dental healthcare, are
inextricably linked to microbial colonization and the formation of pathogenic biofilms …

The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

The Biology of Streptococcus mutans

JA Lemos, SR Palmer, L Zeng, ZT Wen… - Microbiology …, 2019 - Am Soc Microbiol
As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

Oral biofilms: pathogens, matrix, and polymicrobial interactions in microenvironments

WH Bowen, RA Burne, H Wu, H Koo - Trends in microbiology, 2018 - cell.com
Biofilms are microbial communities embedded within an extracellular matrix, forming a
highly organized structure that causes many human infections. Dental caries (tooth decay) is …

Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

The structure of dental plaque microbial communities in the transition from health to dental caries and periodontal disease

AM Valm - Journal of molecular biology, 2019 - Elsevier
The human oral cavity harbors diverse communities of microbes that live as biofilms: highly
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …

Dextran-coated iron oxide nanoparticles as biomimetic catalysts for localized and pH-activated biofilm disruption

PC Naha, Y Liu, G Hwang, Y Huang, S Gubara… - ACS …, 2019 - ACS Publications
Biofilms are surface-attached bacterial communities embedded within an extracellular matrix
that create localized and protected microenvironments. Acidogenic oral biofilms can …

[HTML][HTML] The virulence of Streptococcus mutans and the ability to form biofilms

W Krzyściak, A Jurczak, D Kościelniak… - European Journal of …, 2014 - Springer
In some diseases, a very important role is played by the ability of bacteria to form multi-
dimensional complex structure known as biofilm. The most common disease of the oral …