Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Utilising inorganic nanocarriers for gene delivery

XJ Loh, TC Lee, Q Dou, GR Deen - Biomaterials science, 2016 - pubs.rsc.org
The delivery of genetic materials into cells to elicit cellular responses has been extensively
studied by biomaterials scientists globally. Many materials such as lipids, peptides, viruses …

Impact of gold nanoparticles shape on their cytotoxicity against human osteoblast and osteosarcoma in in vitro model. Evaluation of the safety of use and anti-cancer …

KP Steckiewicz, E Barcinska, A Malankowska… - Journal of Materials …, 2019 - Springer
Due to development of nanotechnology and gold nanoparticles (AuNPs) increasing use in
different areas of medicine, especially in oncology, better understanding of their potential …

Exocytosis of nanoparticles from cells: role in cellular retention and toxicity

R Sakhtianchi, RF Minchin, KB Lee, AM Alkilany… - Advances in colloid and …, 2013 - Elsevier
Over the past decade, nanoparticles (NPs) have been increasingly developed in various
biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug …

Gold nanoparticle mediated cancer immunotherapy

JPM Almeida, ER Figueroa, RA Drezek - … : Nanotechnology, Biology and …, 2014 - Elsevier
Significant progress has been made in the field of cancer immunotherapy, where the goal is
to activate or modulate the body's immune response against cancer. However, current …

[HTML][HTML] Recent advances of drug delivery nanocarriers in osteosarcoma treatment

SY Wang, HZ Hu, XC Qing, ZC Zhang… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …

Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration

W Gu, C Wu, J Chen, Y Xiao - International journal of …, 2013 - Taylor & Francis
Nanotechnology is a vigorous research area and one of its important applications is in
biomedical sciences. Among biomedical applications, targeted drug delivery is one of the …

Effect of size on biological properties of nanoparticles employed in gene delivery

S Prabha, G Arya, R Chandra, B Ahmed… - Artificial cells …, 2016 - Taylor & Francis
Context The size of nanoparticles plays a pivotal role in determining the gene delivery
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …

Histidine-tagged folate-targeted gold nanoparticles for enhanced transgene expression in breast cancer cells in vitro

C Joseph, A Daniels, S Singh, M Singh - Pharmaceutics, 2021 - mdpi.com
Nanotechnology has emerged as a promising treatment strategy in gene therapy, especially
against diseases such as cancer. Gold nanoparticles (AuNPs) are regarded as favorable …

The effects of surface functionality and size of gold nanoparticles on neuronal toxicity, apoptosis, ROS production and cellular/suborgan biodistribution

I Ozcicek, N Aysit, C Cakici, A Aydeger - Materials Science and …, 2021 - Elsevier
Gold nanoparticles are emerging as promising nanomaterials to create nanoscale
therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse …