Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Utilising inorganic nanocarriers for gene delivery
The delivery of genetic materials into cells to elicit cellular responses has been extensively
studied by biomaterials scientists globally. Many materials such as lipids, peptides, viruses …
studied by biomaterials scientists globally. Many materials such as lipids, peptides, viruses …
Impact of gold nanoparticles shape on their cytotoxicity against human osteoblast and osteosarcoma in in vitro model. Evaluation of the safety of use and anti-cancer …
KP Steckiewicz, E Barcinska, A Malankowska… - Journal of Materials …, 2019 - Springer
Due to development of nanotechnology and gold nanoparticles (AuNPs) increasing use in
different areas of medicine, especially in oncology, better understanding of their potential …
different areas of medicine, especially in oncology, better understanding of their potential …
Exocytosis of nanoparticles from cells: role in cellular retention and toxicity
R Sakhtianchi, RF Minchin, KB Lee, AM Alkilany… - Advances in colloid and …, 2013 - Elsevier
Over the past decade, nanoparticles (NPs) have been increasingly developed in various
biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug …
biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug …
Gold nanoparticle mediated cancer immunotherapy
JPM Almeida, ER Figueroa, RA Drezek - … : Nanotechnology, Biology and …, 2014 - Elsevier
Significant progress has been made in the field of cancer immunotherapy, where the goal is
to activate or modulate the body's immune response against cancer. However, current …
to activate or modulate the body's immune response against cancer. However, current …
[HTML][HTML] Recent advances of drug delivery nanocarriers in osteosarcoma treatment
SY Wang, HZ Hu, XC Qing, ZC Zhang… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …
children and adolescence, and chemotherapy is limited for the side effects and development …
Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration
Nanotechnology is a vigorous research area and one of its important applications is in
biomedical sciences. Among biomedical applications, targeted drug delivery is one of the …
biomedical sciences. Among biomedical applications, targeted drug delivery is one of the …
Effect of size on biological properties of nanoparticles employed in gene delivery
Context The size of nanoparticles plays a pivotal role in determining the gene delivery
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …
Histidine-tagged folate-targeted gold nanoparticles for enhanced transgene expression in breast cancer cells in vitro
Nanotechnology has emerged as a promising treatment strategy in gene therapy, especially
against diseases such as cancer. Gold nanoparticles (AuNPs) are regarded as favorable …
against diseases such as cancer. Gold nanoparticles (AuNPs) are regarded as favorable …
The effects of surface functionality and size of gold nanoparticles on neuronal toxicity, apoptosis, ROS production and cellular/suborgan biodistribution
Gold nanoparticles are emerging as promising nanomaterials to create nanoscale
therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse …
therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse …