The toxicological mechanisms of environmental soot (black carbon) and carbon black: focus on oxidative stress and inflammatory pathways

R Niranjan, AK Thakur - Frontiers in immunology, 2017 - frontiersin.org
The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their
underlying mechanisms of toxicity are still poorly understood. Both are formed after the …

Cell-specific DNA methylation signatures in asthma

AA Hudon Thibeault, C Laprise - Genes, 2019 - mdpi.com
Asthma is a complex trait, often associated with atopy. The genetic contribution has been
evidenced by familial occurrence. Genome-wide association studies allowed for associating …

CXCL12/CXCR4 axis is involved in the recruitment of NK cells by HMGB1 contributing to persistent airway inflammation and AHR during the late stage of RSV …

S Chen, W Tang, G Yu, Z Tang, E Liu - Journal of Microbiology, 2023 - Springer
We previously showed that both high-mobility group box-1 (HMGB1) and natural killer (NK)
cells contribute to respiratory syncytial virus (RSV)-induced persistent airway inflammation …

Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma

A Ishimori, N Harada, A Chiba, S Harada… - Allergology …, 2017 - jstage.jst.go.jp
Background: A variety of innate subsets of lymphoid cells such as natural killer (NK) cells,
several populations of innate lymphoid cells (ILCs), and mucosal-associated invariant T …

Allergic Inflammation in Aspergillus fumigatus-Induced Fungal Asthma

S Ghosh, SA Hoselton, JM Schuh - Current allergy and asthma reports, 2015 - Springer
Although fungi are pervasive in many environments, few cause disease in humans. Of these,
Aspergillus fumigatus is particularly well suited to be a pathogen of the human lung. Its …

NK cells contribute to persistent airway inflammation and AHR during the later stage of RSV infection in mice

X Long, J Xie, K Zhao, W Li, W Tang, S Chen… - Medical microbiology …, 2016 - Springer
RSV can lead to persistent airway inflammation and AHR and is intimately associated with
childhood recurrent wheezing and asthma, but the underlying mechanisms remain unclear …

Metabolomic analysis of serum glycerophospholipid levels in eosinophilic and neutrophilic asthma

XY Gai, LJ Zhang, C Chang, CL Guo… - Biomedical and …, 2019 - Elsevier
Objective To compare the serum glycerophospholipid levels in the inflammatory subtypes of
asthma by using targeted metabolomic analysis. Methods Demographic and clinical data …

Beyond CAR-T: The rise of CAR-NK cell therapy in asthma immunotherapy

M Mohammad Taheri, F Javan, M Poudineh… - Journal of Translational …, 2024 - Springer
Asthma poses a major public health burden. While existing asthma drugs manage
symptoms for many, some patients remain resistant. The lack of a cure, especially for severe …

The upregulation of peripheral CD3-CD56+CD16+ natural killer cells correlates with Th1/Th2 imbalance in asthma patients during acute upper respiratory viral …

M Liu, Y Zhang, Y Hu, Z Guo, L Dong - BMC immunology, 2023 - Springer
Purpose The aim of this study is to clarify the changes of peripheral CD3− CD56+ CD16+
NK cells and their correlation with Th1/Th2 immunity profiles in asthma during the phase of …

NK cells in treated HIV-infected children display altered phenotype and function

S Mahapatra, WT Shearer, CG Minard, E Mace… - Journal of Allergy and …, 2019 - Elsevier
Background Chronic HIV infection is known to trigger a population redistribution and
alteration in the functional capacity of natural killer (NK) cells. Because of improved …