[HTML][HTML] Lipid nanoparticles as delivery systems for RNA-based vaccines

BN Aldosari, IM Alfagih, AS Almurshedi - Pharmaceutics, 2021 - mdpi.com
There has been increased interest in the development of RNA-based vaccines for protection
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …

mRNA vaccine delivery using lipid nanoparticles

AM Reichmuth, MA Oberli, A Jaklenec… - Therapeutic …, 2016 - Taylor & Francis
mRNA vaccines elicit a potent immune response including antibodies and cytotoxic T cells.
mRNA vaccines are currently evaluated in clinical trials for cancer immunotherapy …

Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens: toward multicomponent vaccines

D Chatzikleanthous, DT O'Hagan… - Molecular …, 2021 - ACS Publications
Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …

Liposomes as vaccine delivery systems: a review of the recent advances

RA Schwendener - Therapeutic advances in vaccines, 2014 - journals.sagepub.com
Liposomes and liposome-derived nanovesicles such as archaeosomes and virosomes have
become important carrier systems in vaccine development and the interest for liposome …

[HTML][HTML] The multirole of liposomes in therapy and prevention of infectious diseases

R Nisini, N Poerio, S Mariotti, F De Santis… - Frontiers in …, 2018 - frontiersin.org
Liposomes are closed bilayer structures spontaneously formed by hydrated phospholipids
that are widely used as efficient delivery systems for drugs or antigens, due to their capability …

[HTML][HTML] Applications of nanotechnology for immunology

DM Smith, JK Simon, JR Baker Jr - Nature Reviews Immunology, 2013 - nature.com
Nanotechnology uses the unique properties of objects that function as a unit within the
overall size range of 1–1,000 nanometres. The engineering of nanostructure materials …

Nanoparticle-based immunotherapy for cancer

K Shao, S Singha, X Clemente-Casares, S Tsai… - ACS …, 2015 - ACS Publications
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

Liposome and immune system interplay: Challenges and potentials

F Zahednezhad, M Saadat, H Valizadeh… - Journal of Controlled …, 2019 - Elsevier
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

[HTML][HTML] Liposomes as adjuvants and vaccine delivery systems

DS Tretiakova, EL Vodovozova - … Series A: Membrane and Cell Biology, 2022 - Springer
The review considers liposomes as systems of substantial interest as adjuvant carriers in
vaccinology due to their versatility and maximal biocompatibility. Research and …

[HTML][HTML] Harnessing nanoparticles for immune modulation

DR Getts, LD Shea, SD Miller, NJC King - Trends in immunology, 2015 - cell.com
Recent approaches using nanoparticles engineered for immune regulation have yielded
promising results in preclinical models of disease. The number of nanoparticle therapies is …