[HTML][HTML] Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

MT Islam - Neurological research, 2017 - Taylor & Francis
Reactive species play an important role in physiological functions. Overproduction of
reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the …

Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment

Y Esmaeili, Z Yarjanli, F Pakniya, E Bidram… - Journal of Controlled …, 2022 - Elsevier
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

AH Bhat, KB Dar, S Anees, MA Zargar… - Biomedicine & …, 2015 - Elsevier
Mitochondria is one of the main source of oxidative stress (ROS), as it utilizes the oxygen for
the energy production. ROS and RNS are normally generated by tightly regulated enzymes …

Mitochondrial dysfunction and biogenesis in neurodegenerative diseases: pathogenesis and treatment

M Golpich, E Amini, Z Mohamed… - CNS neuroscience & …, 2017 - Wiley Online Library
Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and
characterized by the progressive degeneration of the function and structure of the central …

[HTML][HTML] Oxidative stress, mitochondrial damage and neurodegenerative diseases

C Guo, L Sun, X Chen, D Zhang - Neural regeneration research, 2013 - journals.lww.com
Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of
several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease …

Vitamin D deficiency and diabetes

MJ Berridge - Biochemical Journal, 2017 - portlandpress.com
Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Bipolar disorder diagnosis: challenges and future directions

ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

[HTML][HTML] The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

Oxidative Stress‐Mediated Blood‐Brain Barrier (BBB) Disruption in Neurological Diseases

K Song, Y Li, H Zhang, N An, Y Wei… - Oxidative medicine …, 2020 - Wiley Online Library
The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …