Mesenchymal stem/stromal cell senescence: hallmarks, mechanisms, and combating strategies
Z Weng, Y Wang, T Ouchi, H Liu, X Qiao… - Stem Cells …, 2022 - academic.oup.com
Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine
Abstract Mesenchymal Stem Cells (MSCs) have been shown to be a promising candidate for
cell-based therapy. The therapeutic potential of MSCs, towards tissue repair and wound …
cell-based therapy. The therapeutic potential of MSCs, towards tissue repair and wound …
Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …
fractures and other common injuries. However, the properties of bone change throughout …
Mesenchymal stem cell therapy: hope for patients with systemic lupus erythematosus
A Li, F Guo, Q Pan, S Chen, J Chen, H Liu… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Although previous
studies have demonstrated that SLE is related to the imbalance of cells in the immune …
studies have demonstrated that SLE is related to the imbalance of cells in the immune …
The heterogeneity of mesenchymal stem cells: An important issue to be addressed in cell therapy
J Li, Z Wu, L Zhao, Y Liu, Y Su, X Gong, F Liu… - Stem Cell Research & …, 2023 - Springer
With the continuous improvement of human technology, the medical field has gradually
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …
Experimental strategies of mesenchymal stem cell propagation: adverse events and potential risk of functional changes
K Drela, L Stanaszek, A Nowakowski… - Stem cells …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) are attractive candidates for cell‐based tissue repair
approaches. Hundreds of clinical trials using MSCs have been completed and many others …
approaches. Hundreds of clinical trials using MSCs have been completed and many others …
The cytokine network in acute myeloid leukemia
M Luciano, PW Krenn, J Horejs-Hoeck - Frontiers in immunology, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is a highly heterogeneous malignancy of the blood and bone
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …
Mesenchymal stromal cell senescence in haematological malignancies
N Plakhova, V Panagopoulos, K Vandyke… - Cancer and Metastasis …, 2023 - Springer
Acute myeloid leukaemia (AML), chronic lymphocytic leukaemia (CLL), and multiple
myeloma (MM) are age-related haematological malignancies with defined precursor states …
myeloma (MM) are age-related haematological malignancies with defined precursor states …
[HTML][HTML] Mesenchymal stem cell senescence during aging: From mechanisms to rejuvenation strategies
X Jiang, W Li, L Ge, M Lu - Aging and disease, 2023 - ncbi.nlm.nih.gov
In cell transplantation therapy, mesenchymal stem cells (MSCs) are ideal seed cells due to
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …
Inflammatory signaling pathways in preleukemic and leukemic stem cells
S Hemmati, T Haque, K Gritsman - Frontiers in oncology, 2017 - frontiersin.org
Hematopoietic stem cells (HSCs) are a rare subset of bone marrow cells that usually exist in
a quiescent state, only entering the cell cycle to replenish the blood compartment, thereby …
a quiescent state, only entering the cell cycle to replenish the blood compartment, thereby …