Ischemia-reperfusion (IR) injury is central to the pathology of major cardiovascular diseases,
such as stroke and myocardial infarction. IR injury is mediated by several factors including …

Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …

The morbidity rate of myocardial ischemia and reperfusion has increased in modern society,
and oxidative stress plays a critical role in the pathological process. Nuclear factor E2 …

Reactive oxygen species (ROS), a redox signal, are produced by various enzymatic
reactions and chemical processes, which are essential for many physiological functions and …

Reactive oxygen species (ROS) are products of normal cellular metabolism and are known
to act as second messengers. Under physiological conditions, ROS participate in …

Human health benefits from different polyphenols molecules consumption in the diet,
derived mainly by their common activities in the gastrointestinal tract and at the level of …

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that controls cellular
defense responses against toxic and oxidative stress by modulating the expression of genes …

Reactive oxygen species (ROS) are the initiators in foods and in the stomach of oxidized
dietary lipids, proteins, and lipid-oxidation end-products (ALEs), inducing in humans the …

The consensus cis-regulatory AP-1 (activator protein-1)-like AREs (antioxidant-response
elements) and/or EpREs (electrophile-response elements) allow for differential recruitment …

Scope Flavonoids have well‐known antioxidant, anti‐inflammatory, and anti‐cancer
activities. Isoflavone genistein is considered a potent antioxidant agent against oxidative …