Publisher Summary Combinatorial antibodies will play a significant role in the design of
vaccines and new antiviral agents. Antibodies may also provide a way of determining …

Cytomegalovirus (CMV) is a recognised cause of morbidity and mortality in
immunocompromised individuals. This review will concentrate on recent advances in the …

Glycoprotein B (gB) is the most conserved component of the complex cell-entry machinery of
herpes viruses. A crystal structure of the gB ectodomain from herpes simplex virus type 1 …

Human cytomegalovirus (HCMV) is a widely circulating pathogen that causes severe
disease in immunocompromised patients and infected fetuses. By immortalizing memory B …

Human cytomegalovirus (HCMV) causes congenital disease with long-term morbidity.
HCMV glycoprotein B (gB) transitions irreversibly from a metastable prefusion to a stable …

ABSTRACT A major inhibitor of diagnostic PCR in human plasma was identified and the
mechanism of inhibition was characterized. Human blood was divided by centrifugation into …

Human cytomegalovirus (HCMV), a dsDNA, enveloped virus, is a ubiquitous pathogen that
establishes lifelong latent infections and caused disease in persons with compromised …

We report a novel approach to the generation of monoclonal antibodies based on the
molecular cloning and expression of immunoglobulin variable region cDNAs generated from …

Human cytomegalovirus (HCMV) is an important pathogen in transplant patients and in
congenital infection. Previously, we demonstrated that vaccination with a recombinant viral …

Human cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that
causes severe disease in immunosuppressed patients and infected newborns. Efforts are …