Simple Summary MMP9, due to its proteolytic activity, plays a key role in tumorigenesis by
regulating migration, epithelial-to-mesenchymal transition and survival of cancer cells …

As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a
significant protease which plays vital roles in many biological processes. MMP-9 can cleave …

As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

Matrix metalloproteinases (MMPs) are a group of endopeptidases that play a vital role in the
restoration of damaged skin. Through mediating various cellular events such as …

Clinical and laboratory studies performed over the past few decades have discovered that
dry eye is a chronic inflammatory disease that can be initiated by numerous extrinsic or …

Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …

Research on matrix metalloproteinases (MMPs) and in particular on gelatinase B, alias MMP-
9, has grown exponentially in the decade 2003–2012. Structural details about flexibility of …

Abnormal angiogenesis and vascular remodeling contribute to pathogenesis of a number of
disorders such as tumor, arthritis, atherosclerosis, restenosis, hypertension, and …

Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates
based on a conserved mechanism involving activation of an active site-bound water …

Matrix metalloproteinases (MMPs), also designated matnxms, are a family of related zinc
metalloendopeptidases that function in the turnover of components of the extracellular …