Cancer cells possess a broad spectrum of migration and invasion mechanisms. These
include both individual and collective cell-migration strategies. Cancer therapeutics that are …

Muscle injury induces strong changes in muscle cells and extracellular matrix. Muscle
regeneration after injury has similarities to muscle development during embryogenesis and …

Satellite cells, the predominant stem cell population in adult skeletal muscle, are activated in
response to hypertrophic stimuli and give rise to myogenic progenitor cells (MPCs) within …

How resident stem cells and their immediate progenitors rebuild tissues of pre-injury
organization and size for proportional regeneration is not well understood. Using 3D, time …

Satellite cells are dormant progenitors located at the periphery of skeletal myofibers that can
be triggered to proliferate for both self-renewal and differentiation into myogenic cells. In …

The movement of cells that maintain cell-cell junctions yet protrude along or within tissues is
an important mechanism for cell positioning in morphogenesis, tissue repair and cancer …

Metastasis is the result of cancer cell adaptation to a tissue microenvironment at a distance
from the primary tumor. Metastatic cancer cells require properties that allow them not only to …

Recent loss-of-function studies show that satellite cell depletion does not promote
sarcopenia or unloading-induced atrophy, and does not prevent regrowth. Although …

Skeletal muscle regeneration is a complex process, which is not yet completely understood.
Satellite cells, the skeletal muscle stem cells, become activated after trauma, proliferate, and …

Matrix metalloproteases (MMPs) are key regulatory molecules in the formation, remodeling,
and degradation of extracellular matrix (ECM) components in both physiological and …