Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome
B Lam, M Masellis, M Freedman, DT Stuss… - Alzheimer's research & …, 2013 - Springer
With increasing knowledge of clinical in vivo biomarkers and the pathological intricacies of
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …
White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: a meta‐analysis, systematic …
AD Roseborough, L Saad, M Goodman… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction The primary aim of this paper is to improve the clinical interpretation of white
matter hyperintensities (WMHs) and provide an overarching summary of methodological …
matter hyperintensities (WMHs) and provide an overarching summary of methodological …
Heterogeneity in mild cognitive impairment: Differences in neuropsychological profile and associated white matter lesion pathology
L Delano-Wood, MW Bondi, J Sacco… - Journal of the …, 2009 - cambridge.org
This study examined whether distinct neuropsychological profiles could be delineated in a
sample with Mild Cognitive Impairment (MCI) and whether white matter lesion (WML) burden …
sample with Mild Cognitive Impairment (MCI) and whether white matter lesion (WML) burden …
Subcortical hyperintensities are associated with cognitive decline in patients with mild cognitive impairment
S Debette, S Bombois, A Bruandet, X Delbeuck… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—It has been suggested that subcortical lesions may influence
cognitive performances at early stages of cognitive impairment but not in late stages of …
cognitive performances at early stages of cognitive impairment but not in late stages of …
Association between white matter microstructure, executive functions, and processing speed in older adults: the impact of vascular health
HIL Jacobs, EC Leritz, VJ Williams… - Human brain …, 2013 - Wiley Online Library
Cerebral white matter damage is not only a commonly reported consequence of healthy
aging, but is also associated with cognitive decline and dementia. The aetiology of this …
aging, but is also associated with cognitive decline and dementia. The aetiology of this …
White matter lesions and brain atrophy: more than shared risk factors? A systematic review
APA Appelman, LG Exalto, Y Van Der Graaf… - Cerebrovascular …, 2009 - karger.com
Background: White matter lesions (WML) and brain atrophy are often found on MRI in the
elderly. Shared vascular risk factors may be an explanation for their concomitance …
elderly. Shared vascular risk factors may be an explanation for their concomitance …
Nutrition, inflammation, and cognitive function
J Wärnberg, S Gomez‐Martinez… - Annals of the new …, 2009 - Wiley Online Library
Inflammation, particularly low‐grade chronic inflammation, appears to affect several brain
functions, from early brain development to the development of neurodegenerative disorders …
functions, from early brain development to the development of neurodegenerative disorders …
Correlating cognitive decline with white matter lesion and brain atrophy magnetic resonance imaging measurements in Alzheimer's disease
M Bilello, J Doshi, SA Nabavizadeh… - Journal of …, 2015 - content.iospress.com
Background: Vascular risk factors are increasingly recognized as risks factors for
Alzheimer's disease (AD) and early conversion from mild cognitive impairment (MCI) to …
Alzheimer's disease (AD) and early conversion from mild cognitive impairment (MCI) to …
Cortical thinning related to periventricular and deep white matter hyperintensities
Previous studies showed that white matter hyperintensities (WMH) are related to cognitive
decline in patients with mild cognitive impairment (MCI) or dementia. Moreover …
decline in patients with mild cognitive impairment (MCI) or dementia. Moreover …
Differences in brain volume, hippocampal volume, cerebrovascular risk factors, and apolipoprotein E4 among mild cognitive impairment subtypes
J He, S Farias, O Martinez, B Reed… - Archives of …, 2009 - jamanetwork.com
Objectives To evaluate demographics, magnetic resonance imaging (MRI) measures, and
vascular risk among mild cognitive impairment (MCI) subtypes. Design Cross-sectional …
vascular risk among mild cognitive impairment (MCI) subtypes. Design Cross-sectional …