Visible-light-induced multicomponent cascade cycloaddition involving N-propargyl aromatic amines, diaryliodonium salts and sulfur dioxide: rapid access to 3 …

D Sun, K Yin, R Zhang - Chemical Communications, 2018 - pubs.rsc.org
A visible-light-induced, Eosin Y catalyzed three-component synthesis of 3-
arylsulfonylquinoline derivatives through N-propargyl aromatic amines, diaryliodonium salts …

Exogenous-oxidant-and catalyst-free electrochemical deoxygenative C2 sulfonylation of quinoline N-oxides

M Jiang, Y Yuan, T Wang, Y Xiong, J Li… - Chemical …, 2019 - pubs.rsc.org
An exogenous-oxidant-and catalyst-free electrochemical deoxygenative C2 sulfonylation
reaction has been achieved. By employing quinoline N-oxides as the starting materials, the …

Non-Friedlander Route to Diversely 3-Substituted Quinolines through Au (III)-Catalyzed Annulation Involving Electron-Deficient Alkynes

EI Chikunova, VY Kukushkin, AY Dubovtsev - Organic Letters, 2023 - ACS Publications
Gold (III)-catalyzed annulation of electron-deficient alkynes and 2-amino-arylcarbonyls
provides general modular one-step access to a broad scope of quinoline products. This …

A visible-light-induced oxidative cyclization of N-propargylanilines with sulfinic acids to 3-sulfonated quinoline derivatives without external photocatalysts

Y Zhang, W Chen, X Jia, L Wang, P Li - Chemical Communications, 2019 - pubs.rsc.org
A visible-light-induced oxidative cyclization of N-propargyl anilines with sulfinic acids was
developed under external photocatalyst-free conditions. The reaction provides a …

Structure-based discovery of negative allosteric modulators of the metabotropic glutamate receptor 5

S Kampen, D Rodríguez, M Jørgensen… - ACS Chemical …, 2022 - ACS Publications
Recently determined structures of class CG protein-coupled receptors (GPCRs) revealed the
location of allosteric binding sites and opened new opportunities for the discovery of novel …

Microwave‐Assisted Metal‐Free Rapid Synthesis of C4‐Arylated Quinolines via Povarov Type Multicomponent Reaction

D Chandra, AK Dhiman, R Kumar… - European Journal of …, 2019 - Wiley Online Library
A rapid microwave assisted,(±) camphor‐10‐sulfonic acid (CSA) promoted, Povarov type
multicomponent synthesis of 4‐arylated quinolines from anilines, alkynes, and …

p-TsOH-mediated synthesis of substituted 2, 4-diaryl-3-sulfonylquinolines from functionalized 2-aminobenzophenones and aromatic β-ketosulfones under microwave …

CK Chan, CY Lai, WC Lo, YT Cheng… - Organic & …, 2020 - pubs.rsc.org
This study describes an efficient protocol for the preparation of substituted 2, 4-diaryl-3-
sulfonylquinolines from functionalized 2-aminobenzophenones and aromatic β-ketosulfones …

Semiheterogeneous Photoredox Catalysis: Synthesis of 3-Sulfonylquinolines via Radical Multicomponent Cascade Annulation

X Li, J Jiang, X Chen, WM He - The Journal of Organic Chemistry, 2024 - ACS Publications
An efficient photocatalytic protocol combining heterogeneous semiconductors as
photocatalysts and NHPI as a redox reagent was disclosed. Under this protocol, 3 …

Discovery and preclinical characterization of 3-((4-(4-chlorophenyl)-7-fluoroquinoline-3-yl) sulfonyl) benzonitrile, a novel non-acetylenic metabotropic glutamate …

J Galambos, A Bielik, M Krasavin… - Journal of Medicinal …, 2017 - ACS Publications
Negative allosteric modulators (NAM) of metabotropic glutamate receptor 5 (mGluR5) have
been implicated as a potential pharmacotherapy for a number of psychiatric diseases …

Ball-milling synthesis of sulfonyl quinolines via coupling of haloquinolines with sulfonic acids

XW Liu, JQ Wang, H Ma, Q Zhu, LY Xie - Green Chemistry, 2021 - pubs.rsc.org
An efficient and practical approach for the synthesis of sulfonyl quinolines via ball milling
promoted coupling of haloquinolines with sulfonic acid under metal-, solvent-and additive …