[HTML][HTML] Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

VJ Sydnor, B Larsen, DS Bassett, A Alexander-Bloch… - Neuron, 2021 - cell.com
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

[HTML][HTML] Towards a youth mental health paradigm: a perspective and roadmap

PJ Uhlhaas, CG Davey, UM Mehta, J Shah… - Molecular …, 2023 - nature.com
Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …

Intrinsic activity development unfolds along a sensorimotor–association cortical axis in youth

VJ Sydnor, B Larsen, J Seidlitz, A Adebimpe… - Nature …, 2023 - nature.com
Animal studies of neurodevelopment have shown that recordings of intrinsic cortical activity
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …

Stress and adolescence: Vulnerability and opportunity during a sensitive window of development

LM Sisk, DG Gee - Current Opinion in Psychology, 2022 - Elsevier
Adolescence is a period of dynamic change across multiple systems. Concurrent maturation
of neural, biological, and psychosocial functioning renders adolescence a time of …

Early adversity and development: parsing heterogeneity and identifying pathways of risk and resilience

DG Gee - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Adversity early in life is common and is a major risk factor for the onset of psychopathology.
Delineating the neurodevelopmental pathways by which early adversity affects mental …

Development of frontal GABA and glutamate supports excitation/inhibition balance from adolescence into adulthood

MI Perica, FJ Calabro, B Larsen, W Foran… - Progress in …, 2022 - Elsevier
Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …

[HTML][HTML] Functional connectivity development along the sensorimotor-association axis enhances the cortical hierarchy

AC Luo, VJ Sydnor, A Pines, B Larsen… - Nature …, 2024 - nature.com
Human cortical maturation has been posited to be organized along the sensorimotor-
association axis, a hierarchical axis of brain organization that spans from unimodal …

[HTML][HTML] Neurofunctional correlates of glutamate and GABA imbalance in psychosis: A systematic review

U Zahid, EC Onwordi, EP Hedges, MB Wall… - Neuroscience & …, 2023 - Elsevier
Glutamatergic and GABAergic dysfunction are implicated in the pathophysiology of
schizophrenia. Previous work has shown relationships between glutamate, GABA, and brain …

[HTML][HTML] Impact of stress on excitatory and inhibitory markers of adolescent cognitive critical period plasticity

MI Perica, B Luna - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Adolescence is a time of significant neurocognitive development. Prolonged maturation of
prefrontal cortex (PFC) through adolescence has been found to support improvements in …

[HTML][HTML] Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain

JY Hansen, RD Markello, L Tuominen, M Nørgaard… - NeuroImage, 2022 - Elsevier
Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter
receptors and transporters play a key role in shaping brain function. Due to the lack of …