Artificial intelligence applications in oral cancer and oral dysplasia

CT Viet, M Zhang, N Dharmaraj, GY Li… - … Engineering Part A, 2024 - liebertpub.com
Oral squamous cell carcinoma (OSCC) is a highly unpredictable disease with devastating
mortality rates that have not changed over the past decades, in the face of advancements in …

Demographic bias in misdiagnosis by computational pathology models

A Vaidya, RJ Chen, DFK Williamson, AH Song… - Nature Medicine, 2024 - nature.com
Despite increasing numbers of regulatory approvals, deep learning-based computational
pathology systems often overlook the impact of demographic factors on performance …

Deep learning generates synthetic cancer histology for explainability and education

JM Dolezal, R Wolk, HM Hieromnimon… - NPJ precision …, 2023 - nature.com
Artificial intelligence methods including deep neural networks (DNN) can provide rapid
molecular classification of tumors from routine histology with accuracy that matches or …

Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence

FM Howard, J Dolezal, S Kochanny, G Khramtsova… - NPJ Breast …, 2023 - nature.com
Gene expression-based recurrence assays are strongly recommended to guide the use of
chemotherapy in hormone receptor-positive, HER2-negative breast cancer, but such testing …

Open and reusable deep learning for pathology with WSInfer and QuPath

JR Kaczmarzyk, A O'Callaghan, F Inglis, S Gat… - NPJ Precision …, 2024 - nature.com
Digital pathology has seen a proliferation of deep learning models in recent years, but many
models are not readily reusable. To address this challenge, we developed WSInfer: an open …

Generative adversarial networks accurately reconstruct pan-cancer histology from pathologic, genomic, and radiographic latent features

FM Howard, HM Hieromnimon, S Ramesh… - Science …, 2024 - science.org
Artificial intelligence models have been increasingly used in the analysis of tumor histology
to perform tasks ranging from routine classification to identification of molecular features …

[HTML][HTML] Deep Learning–Based Classification of Early-Stage Mycosis Fungoides and Benign Inflammatory Dermatoses on H&E-Stained Whole-Slide Images: A …

T Doeleman, S Brussee, LM Hondelink… - Journal of Investigative …, 2024 - Elsevier
The diagnosis of early-stage mycosis fungoides (MF) is challenging owing to shared clinical
and histopathological features with benign inflammatory dermatoses. Recent evidence has …

The Quest for the Application of Artificial Intelligence to Whole Slide Imaging: Unique Prospective from New Advanced Tools

G Faa, M Castagnola, L Didaci, F Coghe, M Scartozzi… - Algorithms, 2024 - mdpi.com
The introduction of machine learning in digital pathology has deeply impacted the field,
especially with the advent of whole slide image (WSI) analysis. In this review, we tried to …

Artificial intelligence-based morphologic classification and molecular characterization of neuroblastic tumors from digital histopathology

S Ramesh, E Dyer, M Pomaville, K Doytcheva… - npj Precision …, 2024 - nature.com
A deep learning model using attention-based multiple instance learning (aMIL) and self-
supervised learning (SSL) was developed to perform pathologic classification of …

Developing a low-cost, open-source, locally manufactured workstation and computational pipeline for automated histopathology evaluation using deep learning

D Choudhury, JM Dolezal, E Dyer, S Kochanny… - Ebiomedicine, 2024 - thelancet.com
Background Deployment and access to state-of-the-art precision medicine technologies
remains a fundamental challenge in providing equitable global cancer care in low-resource …